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    lbp-3 Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 3 [ Caenorhabditis elegans ]

    Gene ID: 180615, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lbp-3
    Official Full Name
    Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 3
    Primary source
    WormBase:WBGene00002255
    Locus tag
    CELE_F40F4.4
    See related
    AllianceGenome:WB:WBGene00002255
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lbp-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (3257372..3258155)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Tubulin alpha chain Neighboring gene ncRNA Neighboring gene Fatty acid-binding protein homolog 1 Neighboring gene Fatty acid-binding protein homolog 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lysosome lipid signalling from the periphery to neurons regulates longevity. Savini M, et al. Nat Cell Biol, 2022 Jun. PMID 35681008, Free PMC Article
    2. Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity. Martell J, et al. Cell Chem Biol, 2016 Aug 18. PMID 27499530, Free PMC Article
    3. Secretion of a novel class of iFABPs in nematodes: coordinate use of the Ascaris/Caenorhabditis model systems. Plenefisch J, et al. Mol Biochem Parasitol, 2000 Feb 5. PMID 10693745
    4. ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. O'Rourke EJ, et al. Genes Dev, 2013 Feb 15. PMID 23392608, Free PMC Article
    5. Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans. Van Gilst MR, et al. PLoS Biol, 2005 Feb. PMID 15719061, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 3
    NP_001041250.1
    • Confirmed by transcript evidence
    NP_001379901.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3257372..3258155
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392744.1 → NP_001379901.1  Fatty acid-binding protein homolog 3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20222
      Conserved Domains (1) summary
      cd00742
      Location:26 → 160
      FABP; intracellular fatty acid-binding protein family

    2. NM_001047785.4 → NP_001041250.1  Cytosolic fatty-acid binding proteins domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041250.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q27GU2
      Conserved Domains (1) summary
      cd00742
      Location:11 → 145
      FABP; intracellular fatty acid-binding protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q20222.2

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