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    sfa-1 Branchpoint-bridging protein [ Caenorhabditis elegans ]

    Gene ID: 178486, updated on 27-Dec-2024

    Summary

    Official Symbol
    sfa-1
    Official Full Name
    Branchpoint-bridging protein
    Primary source
    WormBase:WBGene00013808
    Locus tag
    CELE_Y116A8C.32
    See related
    AllianceGenome:WB:WBGene00013808
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity. Involved in alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Orthologous to human SF1 (splicing factor 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See sfa-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (17103825..17110982, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Carbonic anhydrase Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Neighboring gene WSN domain-containing protein;protein of unknown function WSN domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase E Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA-binding protein;Splicing factor U2AF 35 kDa subunit

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables pre-mRNA branch point binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in alternative mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Branchpoint-bridging protein
    NP_503033.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17103825..17110982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070632.7NP_503033.1  Branchpoint-bridging protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503033.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EF97
      Conserved Domains (2) summary
      PTZ00368
      Location:427471
      PTZ00368; universal minicircle sequence binding protein (UMSBP); Provisional
      COG5176
      Location:185422
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    RNA

    1. NR_132466.1 RNA Sequence

      Status: REVIEWED