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    F41H10.5 TLC domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185643, updated on 9-Dec-2024

    Summary

    Official Symbol
    F41H10.5
    Official Full Name
    TLC domain-containing protein
    Primary source
    WormBase:WBGene00018318
    Locus tag
    CELE_F41H10.5
    See related
    AllianceGenome:WB:WBGene00018318
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TLCD1 (TLC domain containing 1) and TLCD2 (TLC domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F41H10.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (5360907..5362158)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene WH2 domain-containing protein Neighboring gene ncRNA Neighboring gene Histone deacetylase 6;UBP-type domain-containing protein Neighboring gene ncRNA Neighboring gene GRIP domain-containing protein

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in membrane assembly  
    involved_in phospholipid homeostasis  
    involved_in plasma membrane organization  
    involved_in regulation of membrane lipid distribution  
    Component Evidence Code Pubs
    located_in membrane  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    TLC domain-containing protein
    NP_500789.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5360907..5362158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068388.3NP_500789.1  TLC domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500789.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20297
      Conserved Domains (1) summary
      smart00724
      Location:56253
      TLC; TRAM, LAG1 and CLN8 homology domains
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