F10D11.6 BPI1 domain-containing protein;Lipid-binding serum glycoprotein C-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F10D11.6
Official Full Name: BPI1 domain-containing protein;Lipid-binding serum glycoprotein C-terminal domain-containing protein
Primary source: WormBase:WBGene00008652
Locus tag: CELE_F10D11.6
See related: AllianceGenome:WB:WBGene00008652
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable lipid binding activity. Predicted to be active in extracellular space. Orthologous to human BPIFC (BPI fold containing family C) and LBP (lipopolysaccharide binding protein). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F10D11.6 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 10

Sequence:: Chromosome: I; NC_003279.8 (8445347..8451001, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F10D11.6 (e-PCR)
- UniSTS:309654

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: BPI1 domain-containing protein;Lipid-binding serum glycoprotein C-terminal domain-containing protein

NP_001250777.1

Confirmed by transcript evidence

NP_001250778.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8445347..8451001 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001263848.3 → NP_001250777.1 BPI1 domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001250777.1

Status: REVIEWED

UniProtKB/TrEMBL

H9G2Z8

Conserved Domains (2) summary

smart00328
Location:66 → 293

BPI1; BPI/LBP/CETP N-terminal domain

cl00188
Location:503 → 801

BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
NM_001263849.3 → NP_001250778.1 Lipid-binding serum glycoprotein C-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001250778.1

Status: REVIEWED

UniProtKB/TrEMBL

H9G2Z9

Conserved Domains (1) summary

cl00188
Location:310 → 608

BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...