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    grl-1 Ground-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182850, updated on 9-Dec-2024

    Summary

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    Official Symbol
    grl-1
    Official Full Name
    Ground-like domain-containing protein
    Primary source
    WormBase:WBGene00001710
    Locus tag
    CELE_C24G6.7
    See related
    AllianceGenome:WB:WBGene00001710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in arcade cell; intestine; nervous system; and tail. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See grl-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (5530725..5533855, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene receptor protein-tyrosine kinase Neighboring gene ncRNA Neighboring gene putative peptidyl-tRNA hydrolase 2 Neighboring gene Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Neighboring gene Biogenesis of lysosome-related organelles complex 1 subunit 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LIN-23-mediated degradation of beta-catenin regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Dreier L, et al. Neuron, 2005 Apr 7. PMID 15820693
    2. Homologs of the Hh signalling network in C. elegans. Bürglin TR, et al. WormBook, 2006 Jan 28. PMID 18050469, Free PMC Article
    3. Comprehensive analysis of gene expression patterns of hedgehog-related genes. Hao L, et al. BMC Genomics, 2006 Oct 31. PMID 17076889, Free PMC Article
    4. Evolution of hedgehog and hedgehog-related genes, their origin from Hog proteins in ancestral eukaryotes and discovery of a novel Hint motif. Bürglin TR. BMC Genomics, 2008 Mar 11. PMID 18334026, Free PMC Article
    5. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Ground-like domain-containing protein
    NP_504460.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5530725..5533855 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072059.2 → NP_504460.1  Ground-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504460.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76386
      Conserved Domains (1) summary
      pfam04155
      Location:275 → 345
      Ground-like; Ground-like domain
    Nucleotide Protein
    Heading Accession and Version

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