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    C03H12.1 PITH domain-containing protein;Thioredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181659, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C03H12.1
    Official Full Name
    PITH domain-containing protein;Thioredoxin domain-containing protein
    Primary source
    WormBase:WBGene00007284
    Locus tag
    CELE_C03H12.1
    See related
    AllianceGenome:WB:WBGene00007284
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cell migration; positive regulation of canonical Wnt signaling pathway; and regulation of protein localization to membrane. Predicted to be located in collagen-containing extracellular matrix and plasma membrane. Predicted to be active in cell surface. Orthologous to human TXNDC11 (thioredoxin domain containing 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C03H12.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    17
    Sequence:
    Chromosome: X; NC_003284.9 (15689449..15696427)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GlyPicaN Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF19 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of protein localization to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PITH domain-containing protein;Thioredoxin domain-containing protein
    NP_001294785.1
    • Partially confirmed by transcript evidence
    NP_001294787.1
    • Partially confirmed by transcript evidence
    NP_001294788.1
    • Confirmed by transcript evidence
    NP_001380130.1
    • Confirmed by transcript evidence
    NP_001380132.1
    • Confirmed by transcript evidence
    NP_510583.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      15689449..15696427
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307859.3 → NP_001294788.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294788.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6FN15
      Conserved Domains (1) summary
      cl00388
      Location:119 → 230
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    2. NM_078182.6 → NP_510583.2  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510583.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECV3
      Conserved Domains (1) summary
      cl00388
      Location:119 → 230
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    3. NM_001392903.1 → NP_001380132.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6FWQ0
      Conserved Domains (1) summary
      cl00388
      Location:25 → 136
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    4. NM_001307858.4 → NP_001294787.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294787.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6EZQ4
      Conserved Domains (1) summary
      cl00388
      Location:25 → 136
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    5. NM_001392904.1 → NP_001380130.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6FCZ6

    6. NM_001307856.4 → NP_001294785.1  PITH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294785.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6F542
    Nucleotide Protein
    Heading Accession and Version

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