rtfo-1 RNA polymerase-associated protein RTF1 homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rtfo-1
Official Full Name: RNA polymerase-associated protein RTF1 homolog
Primary source: WormBase:WBGene00009103
Locus tag: CELE_F25B3.6
See related: AllianceGenome:WB:WBGene00009103
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Located in nucleus. Is expressed in several structures, including intestine; nervous system; non-striated muscle; pharyngeal-intestinal valve; and pharynx. Orthologous to human RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rtfo-1 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 6

Sequence:: Chromosome: V; NC_003283.11 (9580041..9582644, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F25B3.6 (e-PCR)
- UniSTS:321399

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II C-terminal domain phosphoserine binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of Cdc73/Paf1 complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RNA polymerase-associated protein RTF1 homolog

NP_505473.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

9580041..9582644 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073072.5 → NP_505473.1 RNA polymerase-associated protein RTF1 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_505473.1

Status: REVIEWED

UniProtKB/Swiss-Prot

G5EBY0

Conserved Domains (2) summary

smart00719
Location:252 → 360

Plus3; Short conserved domain in transcriptional regulators

COG5296
Location:82 → 503

COG5296; Transcription factor involved in TATA site selection and in elongation by RNA polymerase II [Transcription]