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    pqn-73 Prion-like-(Q/N-rich)-domain-bearing protein [ Caenorhabditis elegans ]

    Gene ID: 174366, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pqn-73
    Official Full Name
    Prion-like-(Q/N-rich)-domain-bearing protein
    Primary source
    WormBase:WBGene00004155
    Locus tag
    CELE_W01C9.3
    See related
    AllianceGenome:WB:WBGene00004155
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in membrane. Predicted to be part of mediator complex. Is expressed in arcade cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pqn-73 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    16
    Sequence:
    Chromosome: II; NC_003280.10 (8540715..8545393)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Reverse transcriptase domain-containing protein Neighboring gene ncRNA Neighboring gene putative 2,4-dienoyl-CoA reductase decr-1.2 [(3E)-enoyl-CoA-producing] Neighboring gene ncRNA Neighboring gene Globin domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oligosaccharides from agar extends lifespan through activation of unfolded protein response via SIR-2.1 in Caenorhabditis elegans. Desaka N, et al. Eur J Nutr, 2022 Dec. PMID 35864340
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Prion-like-(Q/N-rich)-domain-bearing protein
    NP_001391122.1
    • Confirmed by transcript evidence
    NP_001391123.1
    • Partially confirmed by transcript evidence
    NP_001391124.1
    • Partially confirmed by transcript evidence
    NP_001391125.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8540715..8545393
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001404227.1 → NP_001391122.1  Prion-like-(Q/N-rich)-domain-bearing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QCE3, B6VQ50

    2. NM_001404226.1 → NP_001391123.1  Prion-like-(Q/N-rich)-domain-bearing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QGH6, B6VQ51

    3. NM_001404228.1 → NP_001391124.1  Prion-like-(Q/N-rich)-domain-bearing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4Q9C8, B6VQ51

    4. NM_001404229.1 → NP_001391125.1  Prion-like-(Q/N-rich)-domain-bearing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QAW9, B6VQ50
    Nucleotide Protein
    Heading Accession and Version

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