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    HTR1B 5-hydroxytryptamine receptor 1B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716704, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HTR1Bprovided by VGNC
    Official Full Name
    5-hydroxytryptamine receptor 1Bprovided by VGNC
    Primary source
    VGNC:VGNC:73537
    Locus tag
    EGK_15097
    See related
    Ensembl:ENSMMUG00000015717
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HTR1B in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (95570257..95575433)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (75618402..75623579, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 C-like Neighboring gene meiotic double-stranded break formation protein 4 Neighboring gene uncharacterized LOC114677397 Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Watakabe A, et al. Cereb Cortex, 2009 Aug. PMID 19056862, Free PMC Article
    2. Distribution of 5-HT1B and 5-HT1D receptors in the inner ear. Ahn SK, et al. Brain Res, 2010 Jul 30. PMID 20510890, Free PMC Article
    3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. vestibular ganglion cells were immunoreactive for 5-HT(1B) receptors in macaques and rats.
      Title: Distribution of 5-HT1B and 5-HT1D receptors in the inner ear.
    2. found high levels of serotonin receptor 1B mRNA in primary visual cortex (V1) and clear activity-dependent modulatory effects of 5-HT1B receptor agonists on responses of V1 neurons.
      Title: Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled serotonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in bone remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of behavior IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5-hydroxytryptamine receptor 1B
    Names
    serotonin receptor type 1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      95570257..95575433
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136810.2 → XP_014992296.1  5-hydroxytryptamine receptor 1B

      UniProtKB/TrEMBL
      A0A8J8XEK3, F6SFA9, G7MPS2, X2CFC5
      Related
      ENSMMUP00000020635.2, ENSMMUT00000022058.4
      Conserved Domains (1) summary
      cd15333
      Location:46 → 380
      7tmA_5-HT1B_1D; serotonin receptor subtypes 1B and 1D, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

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