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    STAT2 signal transducer and activator of transcription 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712694, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STAT2provided by VGNC
    Official Full Name
    signal transducer and activator of transcription 2provided by VGNC
    Primary source
    VGNC:VGNC:77905
    Locus tag
    EGK_03803
    See related
    Ensembl:ENSMMUG00000000803
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    p113
    Orthologs
    human mouse all
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    Genomic context

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    See STAT2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (55921112..55940827, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (55125665..55145374, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114670869 Neighboring gene canopy FGF signaling regulator 2 Neighboring gene poly(A) specific ribonuclease subunit PAN2 Neighboring gene interleukin 23 subunit alpha Neighboring gene U7 small nuclear RNA Neighboring gene apolipoprotein F Neighboring gene TBCC domain-containing protein 1-like Neighboring gene timeless circadian regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in type I interferon-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal transducer and activator of transcription 2
    Names
    signal transducer and activator of transcription 2, 113kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266927.1 → NP_001253856.1  signal transducer and activator of transcription 2

      See identical proteins and their annotated locations for NP_001253856.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048044
      UniProtKB/TrEMBL
      A0A1D5RB61, A0A8J8YRP5, F6R1P6, G7N7C9
      Related
      ENSMMUP00000001096.2, ENSMMUT00000001167.4
      Conserved Domains (5) summary
      cd10373
      Location:556 → 706
      SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
      smart00964
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain
      cd16852
      Location:141 → 312
      STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
      cl28920
      Location:316 → 475
      STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
      pfam12188
      Location:786 → 838
      STAT2_C; Signal transducer and activator of transcription 2 C terminal

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      55921112..55940827 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151967.2 → XP_015007453.1  signal transducer and activator of transcription 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RB61, A0A8J8YRP5, F6R1P6, G7N7C9
      Conserved Domains (5) summary
      cd10373
      Location:556 → 706
      SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
      smart00964
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain
      cd16852
      Location:141 → 312
      STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
      cl28920
      Location:316 → 475
      STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
      pfam12188
      Location:786 → 838
      STAT2_C; Signal transducer and activator of transcription 2 C terminal

    2. XM_015151966.2 → XP_015007452.1  signal transducer and activator of transcription 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RB61, A0A8J8YRP5, F6R1P6, G7N7C9
      Related
      ENSMMUP00000057552.2, ENSMMUT00000073936.2
      Conserved Domains (5) summary
      cd10373
      Location:556 → 706
      SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
      smart00964
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain
      cd16852
      Location:141 → 312
      STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
      cl28920
      Location:316 → 475
      STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
      pfam12188
      Location:786 → 838
      STAT2_C; Signal transducer and activator of transcription 2 C terminal
    Nucleotide Protein
    Heading Accession and Version

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