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    STAT6 signal transducer and activator of transcription 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714159, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STAT6provided by VGNC
    Official Full Name
    signal transducer and activator of transcription 6provided by VGNC
    Primary source
    VGNC:VGNC:77908
    See related
    Ensembl:ENSMMUG00000017527
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See STAT6 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (56652940..56675153, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (55866972..55889199, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene nuclear envelope integral membrane protein 1 Neighboring gene uncharacterized LOC114670870 Neighboring gene basic proline-rich protein Neighboring gene NGFI-A binding protein 2 Neighboring gene LDL receptor related protein 1 Neighboring gene neurexophilin 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal transducer and activator of transcription 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265997.1 → NP_001252926.1  signal transducer and activator of transcription 6

      See identical proteins and their annotated locations for NP_001252926.1

      Status: PROVISIONAL

      Source sequence(s)
      JV635568
      UniProtKB/TrEMBL
      A0A8J8YKC5, F6UMM2, G7N7E9, H9YVW6, I2CVC3
      Related
      ENSMMUP00000023071.4, ENSMMUT00000024650.4
      Conserved Domains (5) summary
      cd10377
      Location:517 → 646
      SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
      smart00964
      Location:2 → 115
      STAT_int; STAT protein, protein interaction domain
      pfam01017
      Location:124 → 271
      STAT_alpha; STAT protein, all-alpha domain
      pfam02864
      Location:273 → 526
      STAT_bind; STAT protein, DNA binding domain
      pfam14596
      Location:655 → 847
      STAT6_C; STAT6 C-terminal

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      56652940..56675153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152044.2 → XP_015007530.1  signal transducer and activator of transcription 6 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YKC5, F6UMM2, G7N7E9, H9YVW6, I2CVC3
      Related
      ENSMMUP00000073990.1, ENSMMUT00000108000.1
      Conserved Domains (5) summary
      cd10377
      Location:517 → 646
      SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
      smart00964
      Location:2 → 115
      STAT_int; STAT protein, protein interaction domain
      pfam01017
      Location:124 → 271
      STAT_alpha; STAT protein, all-alpha domain
      pfam02864
      Location:273 → 526
      STAT_bind; STAT protein, DNA binding domain
      pfam14596
      Location:655 → 847
      STAT6_C; STAT6 C-terminal

    2. XM_015152045.2 → XP_015007531.1  signal transducer and activator of transcription 6 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YKC5, F6UMM2, G7N7E9, H9YVW6, I2CVC3
      Related
      ENSMMUP00000069419.1, ENSMMUT00000110291.1
      Conserved Domains (5) summary
      cd10377
      Location:517 → 646
      SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
      smart00964
      Location:2 → 115
      STAT_int; STAT protein, protein interaction domain
      pfam01017
      Location:124 → 271
      STAT_alpha; STAT protein, all-alpha domain
      pfam02864
      Location:273 → 526
      STAT_bind; STAT protein, DNA binding domain
      pfam14596
      Location:655 → 847
      STAT6_C; STAT6 C-terminal
    Nucleotide Protein
    Heading Accession and Version

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