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    NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704451, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NHLRC1provided by VGNC
    Official Full Name
    NHL repeat containing E3 ubiquitin protein ligase 1provided by VGNC
    Primary source
    VGNC:VGNC:75229
    Locus tag
    EGK_14504
    See related
    Ensembl:ENSMMUG00000016626
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NHLRC1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (151840994..151845830)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (18519390..18522264, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene lysine demethylase 1B Neighboring gene thiopurine S-methyltransferase Neighboring gene uncharacterized LOC114677690 Neighboring gene kinesin family member 13A Neighboring gene small nuclear ribonucleoprotein E pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation repressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase NHLRC1
    Names
    NHL repeat containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      151840994..151845830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001097330.4 → XP_001097330.1  E3 ubiquitin-protein ligase NHLRC1

      See identical proteins and their annotated locations for XP_001097330.1

      UniProtKB/TrEMBL
      A0A8J8XAW9, F6TPH3, G7MQT2
      Related
      ENSMMUP00000021863.1, ENSMMUT00000023366.3
      Conserved Domains (3) summary
      cd14961
      Location:118 → 391
      NHL_TRIM32_like; NHL repeat domain of the tripartite motif-containing protein 32 (TRIM32) and related proteins
      pfam14634
      Location:25 → 73
      zf-RING_5; zinc-RING finger domain
      sd00039
      Location:178 → 211
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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