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    PAN2 poly(A) specific ribonuclease subunit PAN2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712478, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PAN2provided by VGNC
    Official Full Name
    poly(A) specific ribonuclease subunit PAN2provided by VGNC
    Primary source
    VGNC:VGNC:100085
    Locus tag
    EGK_03800
    See related
    Ensembl:ENSMMUG00000013482
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PAN2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (55892640..55911608, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (55095973..55115210, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene citrate synthase Neighboring gene uncharacterized LOC114670869 Neighboring gene canopy FGF signaling regulator 2 Neighboring gene interleukin 23 subunit alpha Neighboring gene signal transducer and activator of transcription 2 Neighboring gene U7 small nuclear RNA Neighboring gene apolipoprotein F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables poly(A)-specific ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of PAN complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PAN2-PAN3 deadenylation complex catalytic subunit PAN2
    Names
    PAB-dependent poly(A)-specific ribonuclease subunit 2
    PAN2 poly(A) specific ribonuclease subunit homolog
    XP_015007494.1
    XP_028685445.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      55892640..55911608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152008.2 → XP_015007494.1  PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1

      UniProtKB/TrEMBL
      G7N7C6, I0FWV6
      Related
      ENSMMUP00000017721.3, ENSMMUT00000018923.4
      Conserved Domains (3) summary
      cd06143
      Location:970 → 1143
      PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
      pfam13423
      Location:516 → 893
      UCH_1; Ubiquitin carboxyl-terminal hydrolase
      cl29593
      Location:204 → 357
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_028829612.1 → XP_028685445.1  PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X2

      UniProtKB/TrEMBL
      G7N7C6
      Conserved Domains (3) summary
      cd06143
      Location:969 → 1142
      PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
      pfam13423
      Location:516 → 892
      UCH_1; Ubiquitin carboxyl-terminal hydrolase
      cl29593
      Location:204 → 357
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. XR_001448048.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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    Research Materials