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    GFAP glial fibrillary acidic protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712941, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GFAPprovided by VGNC
    Official Full Name
    glial fibrillary acidic proteinprovided by VGNC
    Primary source
    VGNC:VGNC:72913
    See related
    Ensembl:ENSMMUG00000013115
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GFAP in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (56169389..56180984, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (50790508..50802078, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene elongation factor Tu GTP binding domain containing 2 Neighboring gene coiled-coil domain containing 103 Neighboring gene family with sequence similarity 187 member A Neighboring gene kinesin family member 18B Neighboring gene complement C1q like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus. Haley GE, et al. Age (Dordr), 2010 Sep. PMID 20640549, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. There was significantly more GFAP immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.
      Title: Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intermediate filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of chaperone-mediated autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glial fibrillary acidic protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      56169389..56180984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015119892.2 → XP_014975378.1  glial fibrillary acidic protein isoform X2

      Related
      ENSMMUP00000049963.2, ENSMMUT00000076046.2
      Conserved Domains (2) summary
      pfam00038
      Location:138 → 446
      Filament; Intermediate filament protein
      pfam04732
      Location:73 → 136
      Filament_head; Intermediate filament head (DNA binding) region

    2. XM_028836604.1 → XP_028692437.1  glial fibrillary acidic protein isoform X1

      Related
      ENSMMUP00000046183.2, ENSMMUT00000077212.2
      Conserved Domains (2) summary
      pfam04732
      Location:71 → 136
      Filament_head; Intermediate filament head (DNA binding) region
      pfam00038
      Location:138 → 446
      Filament; Intermediate filament protein
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials