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    C8A complement C8 alpha chain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716114, updated on 17-Aug-2024

    Summary

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    Official Symbol
    C8Aprovided by VGNC
    Official Full Name
    complement C8 alpha chainprovided by VGNC
    Primary source
    VGNC:VGNC:70479
    See related
    Ensembl:ENSMMUG00000022992
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See C8A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (167506643..167569823, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (56527874..56591052)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene DAB adaptor protein 1 Neighboring gene uncharacterized LOC114672243 Neighboring gene uncharacterized LOC106998846 Neighboring gene complement C8 beta chain Neighboring gene FYN binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of membrane attack complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    complement component C8 alpha chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      167506643..167569823 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001114403.3 → XP_001114403.2  complement component C8 alpha chain

      UniProtKB/TrEMBL
      F6U5Q9, G7MH96
      Related
      ENSMMUP00000030275.4, ENSMMUT00000032357.4
      Conserved Domains (3) summary
      smart00209
      Location:551 → 584
      TSP1; Thrombospondin type 1 repeats
      smart00457
      Location:289 → 492
      MACPF; membrane-attack complex / perforin
      cd00112
      Location:96 → 130
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    Nucleotide Protein
    Heading Accession and Version

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