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    KCNJ2 potassium inwardly rectifying channel subfamily J member 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574189, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KCNJ2provided by VGNC
    Official Full Name
    potassium inwardly rectifying channel subfamily J member 2provided by VGNC
    Primary source
    VGNC:VGNC:73988
    Locus tag
    EGK_08925
    See related
    Ensembl:ENSMMUG00000056768
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    IRK1
    Orthologs
    human mouse all
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    Genomic context

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    See KCNJ2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (66457894..66470542)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (63495523..63510480)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene potassium inwardly rectifying channel subfamily J member 16 Neighboring gene uncharacterized LOC114673183 Neighboring gene calmodulin-like Neighboring gene uncharacterized LOC114673184 Neighboring gene uncharacterized LOC106994117

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family. Rae JL, et al. Exp Eye Res, 1998 Mar. PMID 9533862
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inward rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inward rectifier potassium channel 2
    Names
    IRK-1
    cardiac inward rectifier potassium channel
    inward rectifier K(+) channel Kir2.1
    potassium channel, inwardly rectifying subfamily J member 2
    potassium voltage-gated channel subfamily J member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032859.1 → NP_001028031.1  inward rectifier potassium channel 2

      See identical proteins and their annotated locations for NP_001028031.1

      Status: PROVISIONAL

      Source sequence(s)
      AF021135
      UniProtKB/Swiss-Prot
      P63253
      UniProtKB/TrEMBL
      A0A5F7ZQB0, A0A8J8Y7B3, G7NJD1, H9FU65
      Conserved Domains (3) summary
      pfam01007
      Location:48 → 186
      IRK; Inward rectifier potassium channel
      pfam08466
      Location:1 → 47
      IRK_N; Inward rectifier potassium channel N-terminal
      pfam17655
      Location:193 → 366
      IRK_C; Inward rectifier potassium channel C-terminal domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      66457894..66470542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015120210.2 → XP_014975696.1  inward rectifier potassium channel 2 isoform X1

      UniProtKB/Swiss-Prot
      P63253
      UniProtKB/TrEMBL
      A0A5F7ZQB0, A0A8J8Y7B3, G7NJD1, H9FU65
      Related
      ENSMMUP00000080191.1, ENSMMUT00000079387.1
      Conserved Domains (3) summary
      pfam01007
      Location:48 → 186
      IRK; Inward rectifier potassium channel
      pfam08466
      Location:1 → 47
      IRK_N; Inward rectifier potassium channel N-terminal
      pfam17655
      Location:193 → 366
      IRK_C; Inward rectifier potassium channel C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P63253.1 GenPept UniProtKB/Swiss-Prot:P63253

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