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    IL4R interleukin 4 receptor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705404, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IL4Rprovided by VGNC
    Official Full Name
    interleukin 4 receptorprovided by VGNC
    Primary source
    VGNC:VGNC:73730
    See related
    Ensembl:ENSMMUG00000004666
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IL4R in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (25658898..25709063)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (26104987..26155359)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene NSE1 homolog, SMC5-SMC6 complex component Neighboring gene uncharacterized LOC106994982 Neighboring gene uncharacterized LOC106994981 Neighboring gene interleukin 21 receptor Neighboring gene general transcription factor IIIC subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in production of molecular mediator involved in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-4 receptor subunit alpha
    Names
    interleukin 4 receptor alpha chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      25658898..25709063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841522.1 → XP_028697355.1  interleukin-4 receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      H9Z8K3
      Conserved Domains (2) summary
      cd00063
      Location:130 → 226
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09238
      Location:39 → 128
      IL4Ra_N; Interleukin-4 receptor alpha chain, N-terminal

    2. XM_015125833.2 → XP_014981319.2  interleukin-4 receptor subunit alpha isoform X2

      UniProtKB/TrEMBL
      F6RUR0, H9Z8K3
      Related
      ENSMMUP00000006203.4, ENSMMUT00000006594.4
      Conserved Domains (2) summary
      cd00063
      Location:123 → 219
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09238
      Location:32 → 121
      IL4Ra_N; Interleukin-4 receptor alpha chain, N-terminal
    Nucleotide Protein
    Heading Accession and Version

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