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    USP45 ubiquitin specific peptidase 45 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694340, updated on 17-Aug-2024

    Summary

    Official Symbol
    USP45provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 45provided by VGNC
    Primary source
    VGNC:VGNC:79233
    See related
    Ensembl:ENSMMUG00000005929
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See USP45 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (73775812..73858349)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (97940960..98022910, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S3 pseudogene Neighboring gene thiosulfate sulfurtransferase like domain containing 3 Neighboring gene cyclin C Neighboring gene PNN interacting serine and arginine rich protein Neighboring gene coenzyme Q3, methyltransferase

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    Ubiquitin carboxyl-terminal hydrolase 45; ubiquitin carboxyl-terminal hydrolase 45
    XP_001085248.1
    XP_014992457.1
    XP_028703155.1
    XP_028703156.1
    XP_028703157.1
    XP_028703158.1
    XP_028703159.1
    XP_028703160.1
    XP_028703161.1
    XP_028703162.1
    XP_028703163.1
    XP_028703164.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      73775812..73858349
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001085248.4XP_001085248.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X1

      See identical proteins and their annotated locations for XP_001085248.1

      UniProtKB/TrEMBL
      F6V497
      Related
      ENSMMUP00000007804.4, ENSMMUT00000008303.4
      Conserved Domains (3) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02667
      Location:604812
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    2. XM_028847327.1XP_028703160.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X4

      Conserved Domains (2) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    3. XM_028847329.1XP_028703162.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X6

      Conserved Domains (1) summary
      cd02667
      Location:243451
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    4. XM_028847325.1XP_028703158.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X3

      Conserved Domains (3) summary
      COG5207
      Location:5333
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02667
      Location:546754
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:192330
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    5. XM_028847326.1XP_028703159.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X4

      Conserved Domains (2) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    6. XM_028847322.1XP_028703155.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X1

      UniProtKB/TrEMBL
      F6V497
      Conserved Domains (3) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02667
      Location:604812
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    7. XM_028847323.1XP_028703156.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X2

      Conserved Domains (4) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      COG5560
      Location:192784
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02667
      Location:604783
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    8. XM_028847324.1XP_028703157.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X3

      Conserved Domains (3) summary
      COG5207
      Location:5333
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02667
      Location:546754
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:192330
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    9. XM_028847328.1XP_028703161.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X5

      Conserved Domains (2) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    10. XM_028847331.1XP_028703164.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X7

      Conserved Domains (2) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    11. XM_015136971.2XP_014992457.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X1

      UniProtKB/TrEMBL
      F6V497
      Conserved Domains (3) summary
      COG5207
      Location:5359
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02667
      Location:604812
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:192388
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    12. XM_028847330.1XP_028703163.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X6

      Conserved Domains (1) summary
      cd02667
      Location:243451
      Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    RNA

    1. XR_003728871.1 RNA Sequence