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    HELT helt bHLH transcription factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694986, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HELTprovided by VGNC
    Official Full Name
    helt bHLH transcription factorprovided by VGNC
    Primary source
    VGNC:VGNC:73264
    Locus tag
    EGK_16283
    See related
    Ensembl:ENSMMUG00000001081
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HELT in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (182327305..182329408)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (185470627..185472723)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678456 Neighboring gene uncharacterized LOC114678457 Neighboring gene uncharacterized LOC106998607 Neighboring gene solute carrier family 25 member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anterior/posterior pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hairy and enhancer of split-related protein HELT
    Names
    HES/HEY-like transcription factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193735.1 → NP_001180664.1  hairy and enhancer of split-related protein HELT

      See identical proteins and their annotated locations for NP_001180664.1

      Status: INFERRED

      Source sequence(s)
      QNVO02000369
      UniProtKB/TrEMBL
      A0A8J8YG37, F6QM82, G7MSE2
      Related
      ENSMMUP00000001440.2, ENSMMUT00000001533.4
      Conserved Domains (2) summary
      pfam00010
      Location:57 → 151
      HLH; Helix-loop-helix DNA-binding domain
      pfam07527
      Location:172 → 212
      Hairy_orange; Hairy Orange

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      182327305..182329408
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002804279.3 → XP_002804325.1  hairy and enhancer of split-related protein HELT isoform X1

      Conserved Domains (2) summary
      pfam00010
      Location:13 → 66
      HLH; Helix-loop-helix DNA-binding domain
      pfam07527
      Location:87 → 127
      Hairy_orange; Hairy Orange

    2. XM_015139559.2 → XP_014995045.1  hairy and enhancer of split-related protein HELT isoform X2

      Conserved Domains (2) summary
      pfam00010
      Location:13 → 66
      HLH; Helix-loop-helix DNA-binding domain
      pfam07527
      Location:86 → 126
      Hairy_orange; Hairy Orange
    Nucleotide Protein
    Heading Accession and Version

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