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    TPMT thiopurine S-methyltransferase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704564, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TPMTprovided by VGNC
    Official Full Name
    thiopurine S-methyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:83512
    See related
    Ensembl:ENSMMUG00000016627
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TPMT in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (151812559..151836374)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (18528853..18552583, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene DEK proto-oncogene Neighboring gene lysine demethylase 1B Neighboring gene NHL repeat containing E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized LOC114677690

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thiopurine S-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thiopurine S-methyltransferase
    XP_014991106.1
    XP_014991107.1
    XP_028703648.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      151812559..151836374
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135620.2 → XP_014991106.1  thiopurine S-methyltransferase

      UniProtKB/TrEMBL
      F6TPF9, H9FMR1
      Related
      ENSMMUP00000062592.1, ENSMMUT00000093767.1
      Conserved Domains (1) summary
      pfam05724
      Location:24 → 245
      TPMT; Thiopurine S-methyltransferase (TPMT)

    2. XM_028847815.1 → XP_028703648.1  thiopurine S-methyltransferase

      UniProtKB/TrEMBL
      F6TPF9, H9FMR1
      Related
      ENSMMUP00000021865.2, ENSMMUT00000023368.4
      Conserved Domains (1) summary
      pfam05724
      Location:24 → 245
      TPMT; Thiopurine S-methyltransferase (TPMT)

    3. XM_015135621.2 → XP_014991107.1  thiopurine S-methyltransferase

      UniProtKB/TrEMBL
      F6TPF9, H9FMR1
      Conserved Domains (1) summary
      pfam05724
      Location:24 → 245
      TPMT; Thiopurine S-methyltransferase (TPMT)
    Nucleotide Protein
    Heading Accession and Version

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