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    M6PR mannose-6-phosphate receptor, cation dependent [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716696, updated on 17-Aug-2024

    Summary

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    Official Symbol
    M6PRprovided by VGNC
    Official Full Name
    mannose-6-phosphate receptor, cation dependentprovided by VGNC
    Primary source
    VGNC:VGNC:74469
    See related
    Ensembl:ENSMMUG00000017846
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See M6PR in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (10800978..10810919)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (9244899..9254842, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene voltage-dependent anion-selective channel protein 2 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene killer cell lectin like receptor G1 Neighboring gene polyhomeotic homolog 1 Neighboring gene uncharacterized LOC114670784 Neighboring gene proline-rich protein 13 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell. Díaz-Salinas MA, et al. J Virol, 2014 Apr. PMID 24501398, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.
      Title: Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein targeting to lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cation-dependent mannose-6-phosphate receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      10800978..10810919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151036.2 → XP_015006522.1  cation-dependent mannose-6-phosphate receptor isoform X1

      UniProtKB/TrEMBL
      F7DKQ6
      Related
      ENSMMUP00000023466.4, ENSMMUT00000025082.4
      Conserved Domains (1) summary
      pfam02157
      Location:56 → 309
      Man-6-P_recep; Mannose-6-phosphate receptor

    2. XM_028829251.1 → XP_028685084.1  cation-dependent mannose-6-phosphate receptor isoform X3

      UniProtKB/TrEMBL
      A0A8J8XLJ5, G7N5X6, I0FRP8
      Conserved Domains (1) summary
      pfam02157
      Location:25 → 278
      Man-6-P_recep; Mannose-6-phosphate receptor

    3. XM_028829252.1 → XP_028685085.1  cation-dependent mannose-6-phosphate receptor isoform X3

      UniProtKB/TrEMBL
      A0A8J8XLJ5, G7N5X6, I0FRP8
      Conserved Domains (1) summary
      pfam02157
      Location:25 → 278
      Man-6-P_recep; Mannose-6-phosphate receptor

    4. XM_001114044.4 → XP_001114044.2  cation-dependent mannose-6-phosphate receptor isoform X2

      Conserved Domains (1) summary
      pfam02157
      Location:2 → 279
      Man-6-P_recep; Mannose-6-phosphate receptor
    Nucleotide Protein
    Heading Accession and Version

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