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    LOC706619 transducin-like enhancer protein 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706619, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC706619
    Gene description
    transducin-like enhancer protein 4
    See related
    Ensembl:ENSMMUG00000023365
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    TLE4
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    Genomic context

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    See LOC706619 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (94929390..95086173)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (95888953..96045713)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106993809 Neighboring gene uncharacterized LOC106993807 Neighboring gene uncharacterized LOC114672825 Neighboring gene uncharacterized LOC114672826 Neighboring gene serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform pseudogene Neighboring gene uncharacterized LOC106993808

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transducin-like enhancer protein 4
    Names
    transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      94929390..95086173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117957.2 → XP_014973443.1  transducin-like enhancer protein 4 isoform X1

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:519 → 803
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:523 → 562
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 139
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    2. XM_001103112.4 → XP_001103112.2  transducin-like enhancer protein 4 isoform X9

      UniProtKB/TrEMBL
      H9EUD9
      Conserved Domains (3) summary
      cd00200
      Location:487 → 771
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:491 → 530
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 139
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    3. XM_001103029.4 → XP_001103029.2  transducin-like enhancer protein 4 isoform X2

      UniProtKB/TrEMBL
      F6VCD6, F7E896
      Related
      ENSMMUP00000030756.4, ENSMMUT00000032871.4
      Conserved Domains (3) summary
      cd00200
      Location:518 → 802
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:522 → 561
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 138
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    4. XM_015117961.2 → XP_014973447.1  transducin-like enhancer protein 4 isoform X10

      UniProtKB/TrEMBL
      F6PZC8, H9EUD9, H9FZ39
      Related
      ENSMMUP00000006151.4, ENSMMUT00000006540.4
      Conserved Domains (3) summary
      cd00200
      Location:486 → 770
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:490 → 529
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 138
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    5. XM_015117958.2 → XP_014973444.1  transducin-like enhancer protein 4 isoform X7

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:494 → 778
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:498 → 537
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 103
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    6. XM_015117962.2 → XP_014973448.1  transducin-like enhancer protein 4 isoform X16

      UniProtKB/TrEMBL
      H9EUD9
      Conserved Domains (3) summary
      cd00200
      Location:462 → 746
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:466 → 505
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 103
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    7. XM_015117959.2 → XP_014973445.1  transducin-like enhancer protein 4 isoform X8

      UniProtKB/TrEMBL
      F6VCD6
      Related
      ENSMMUP00000004960.4, ENSMMUT00000005265.4
      Conserved Domains (3) summary
      cd00200
      Location:493 → 777
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:497 → 536
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 113
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    8. XM_001102592.4 → XP_001102592.2  transducin-like enhancer protein 4 isoform X17

      UniProtKB/TrEMBL
      H9EUD9
      Conserved Domains (3) summary
      cd00200
      Location:461 → 745
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:465 → 504
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 109
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    9. XM_028835273.1 → XP_028691106.1  transducin-like enhancer protein 4 isoform X5

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:498 → 782
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:502 → 541
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 118
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    10. XM_028835278.1 → XP_028691111.1  transducin-like enhancer protein 4 isoform X14

      UniProtKB/TrEMBL
      H9EUD9
      Conserved Domains (3) summary
      cd00200
      Location:466 → 750
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:470 → 509
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 118
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    11. XM_028835274.1 → XP_028691107.1  transducin-like enhancer protein 4 isoform X6

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:497 → 781
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:501 → 540
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 117
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    12. XM_028835279.1 → XP_028691112.1  transducin-like enhancer protein 4 isoform X15

      UniProtKB/TrEMBL
      H9EUD9
      Conserved Domains (3) summary
      cd00200
      Location:465 → 749
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:469 → 508
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:16 → 117
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    13. XM_028835271.1 → XP_028691104.1  transducin-like enhancer protein 4 isoform X3

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:504 → 788
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:508 → 547
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 124
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    14. XM_028835272.1 → XP_028691105.1  transducin-like enhancer protein 4 isoform X4

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:503 → 787
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:507 → 546
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 123
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    15. XM_028835277.1 → XP_028691110.1  transducin-like enhancer protein 4 isoform X13

      UniProtKB/TrEMBL
      H9EUD9
      Conserved Domains (3) summary
      cd00200
      Location:471 → 755
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:475 → 514
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 123
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    16. XM_028835275.1 → XP_028691108.1  transducin-like enhancer protein 4 isoform X11

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:479 → 763
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:483 → 522
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 88
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    17. XM_028835276.1 → XP_028691109.1  transducin-like enhancer protein 4 isoform X12

      UniProtKB/TrEMBL
      F6VCD6
      Conserved Domains (3) summary
      cd00200
      Location:478 → 762
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:482 → 521
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:8 → 94
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    18. XM_028835280.1 → XP_028691113.1  transducin-like enhancer protein 4 isoform X18

      UniProtKB/TrEMBL
      G7NGD8
      Conserved Domains (3) summary
      cd00200
      Location:398 → 682
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:402 → 441
      7WD40; WD40 repeat [structural motif]
      pfam03920
      Location:1 → 18
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    19. XM_028835281.1 → XP_028691114.1  transducin-like enhancer protein 4 isoform X19

      UniProtKB/TrEMBL
      G7NGD8
      Conserved Domains (2) summary
      cd00200
      Location:397 → 681
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:401 → 440
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
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