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    LAMA1 laminin subunit alpha 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 722472, updated on 5-Mar-2024

    Summary

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    Gene symbol
    LAMA1
    Gene description
    laminin subunit alpha 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LAMA1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    63
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (68041200..68206803, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (2471096..2639119)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 28 Neighboring gene uncharacterized LOC106994419 Neighboring gene uncharacterized LOC106994418 Neighboring gene solute carrier family 25 member 51-like Neighboring gene leucine rich repeat containing 30

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in blood vessel morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in camera-type eye development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit alpha-1; LOW QUALITY PROTEIN: laminin subunit alpha-1
    Names
    laminin, alpha 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      68041200..68206803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001118617.4 → XP_001118617.4  LOW QUALITY PROTEIN: laminin subunit alpha-1

      Conserved Domains (11) summary
      smart00136
      Location:20 → 272
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:906 → 952
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1217 → 1348
      LamB; Laminin B domain
      smart00282
      Location:2145 → 2284
      LamG; Laminin G domain
      cd00055
      Location:852 → 904
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:2311 → 2467
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1725 → 2061
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2015 → 2149
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1579 → 1834
      Laminin_I; Laminin Domain I
      pfam00053
      Location:458 → 504
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2747 → 2876
      Laminin_G_1; Laminin G domain
    Nucleotide Protein
    Heading Accession and Version

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