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    KLHL3 kelch like family member 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713123, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KLHL3provided by VGNC
    Official Full Name
    kelch like family member 3provided by VGNC
    Primary source
    VGNC:VGNC:74186
    Locus tag
    EGK_16887
    See related
    Ensembl:ENSMMUG00000011925
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KLHL3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (135011433..135128755, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (135321676..135438857, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678913 Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 Neighboring gene cyclin-dependent kinase 1 pseudogene Neighboring gene microRNA mir-874 Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A0

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in renal sodium ion absorption IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch-like protein 3
    Names
    kelch-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265837.2 → NP_001252766.1  kelch-like protein 3

      See identical proteins and their annotated locations for NP_001252766.1

      Status: PROVISIONAL

      Source sequence(s)
      JU471766
      UniProtKB/TrEMBL
      H9YY04
      Related
      ENSMMUP00000065781.1, ENSMMUT00000081233.1
      Conserved Domains (5) summary
      smart00612
      Location:491 → 537
      Kelch; Kelch domain
      PHA03098
      Location:47 → 566
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:431 → 476
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:40 → 144
      BTB; BTB/POZ domain
      pfam07707
      Location:152 → 254
      BACK; BTB And C-terminal Kelch

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      135011433..135128755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849268.1 → XP_028705101.1  kelch-like protein 3 isoform X2

      Conserved Domains (3) summary
      PHA03098
      Location:21 → 490
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:355 → 400
      Kelch; KELCH repeat [structural motif]
      cd18513
      Location:71 → 200
      BACK_KLHL3; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 3 (KLHL3)

    2. XM_015140875.2 → XP_014996361.1  kelch-like protein 3 isoform X1

      Conserved Domains (6) summary
      smart00612
      Location:491 → 537
      Kelch; Kelch domain
      PHA03098
      Location:47 → 566
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:431 → 476
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:40 → 144
      BTB; BTB/POZ domain
      pfam01344
      Location:527 → 571
      Kelch_1; Kelch motif
      pfam07707
      Location:152 → 254
      BACK; BTB And C-terminal Kelch

    RNA

    1. XR_001445535.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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