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    NADSYN1 NAD synthetase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707652, updated on 17-Aug-2024

    Summary

    Official Symbol
    NADSYN1provided by VGNC
    Official Full Name
    NAD synthetase 1provided by VGNC
    Primary source
    VGNC:VGNC:75048
    See related
    Ensembl:ENSMMUG00000011977
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See NADSYN1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (3454041..3506830, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (3225336..3274872, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase II subunit RPB1-like Neighboring gene histidine-rich glycoprotein-like Neighboring gene zinc finger protein 195-like Neighboring gene 7-dehydrocholesterol reductase Neighboring gene actin epsilon 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables NAD+ synthase (glutamine-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables glutaminase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in NAD biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    glutamine-dependent NAD(+) synthetase
    XP_014968885.1
    XP_014968886.1
    XP_028688918.1
    XP_028688919.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      3454041..3506830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028833086.1XP_028688919.1  glutamine-dependent NAD(+) synthetase isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZDM4
      Conserved Domains (1) summary
      PLN02339
      Location:143707
      PLN02339; NAD+ synthase (glutamine-hydrolysing)
    2. XM_015113400.2XP_014968886.1  glutamine-dependent NAD(+) synthetase isoform X3

      UniProtKB/TrEMBL
      F7B8T2
      Conserved Domains (3) summary
      cd07570
      Location:6250
      GAT_Gln-NAD-synth; Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases)
      PLN02339
      Location:3651
      PLN02339; NAD+ synthase (glutamine-hydrolysing)
      cd00553
      Location:279602
      NAD_synthase; NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD ...
    3. XM_015113399.2XP_014968885.1  glutamine-dependent NAD(+) synthetase isoform X2

      UniProtKB/TrEMBL
      H9EWR4
      Related
      ENSMMUP00000037718.3, ENSMMUT00000044702.3
      Conserved Domains (3) summary
      cd07570
      Location:6298
      GAT_Gln-NAD-synth; Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases)
      PLN02339
      Location:3699
      PLN02339; NAD+ synthase (glutamine-hydrolysing)
      cd00553
      Location:327650
      NAD_synthase; NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD ...
    4. XM_028833085.1XP_028688918.1  glutamine-dependent NAD(+) synthetase isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZDM4
      Related
      ENSMMUP00000062707.1, ENSMMUT00000097290.1
      Conserved Domains (1) summary
      PLN02339
      Location:143707
      PLN02339; NAD+ synthase (glutamine-hydrolysing)