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    LOC714689 nuclear factor NF-kappa-B p100 subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714689, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC714689
    Gene description
    nuclear factor NF-kappa-B p100 subunit
    See related
    Ensembl:ENSMMUG00000002990
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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    Genomic context

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    See LOC714689 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 Unlocalized Scaffold NW_021160234.1 (40453..48445, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (98110785..98118760)

    NW_021160234.1Genomic Context describing neighboring genes Neighboring gene CUE domain containing 2 Neighboring gene F-box and leucine rich repeat protein 15 Neighboring gene PH and SEC7 domain-containing protein 1 Neighboring gene Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in non-canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to cytokine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor NF-kappa-B p100 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NW_021160234.1 Reference Mmul_10 Primary Assembly

      Range
      40453..48445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148078.2 → XP_015003564.2  nuclear factor NF-kappa-B p100 subunit isoform X4

      UniProtKB/TrEMBL
      F7GVV0, H9YVH7
      Related
      ENSMMUP00000003997.4, ENSMMUT00000004237.4
      Conserved Domains (5) summary
      cd07934
      Location:38 → 221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:774 → 849
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      PHA03095
      Location:459 → 705
      PHA03095; ankyrin-like protein; Provisional
      cd01177
      Location:228 → 327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:599 → 630
      ANK; ANK repeat [structural motif]

    2. XM_015148077.2 → XP_015003563.2  nuclear factor NF-kappa-B p100 subunit isoform X4

      UniProtKB/TrEMBL
      F7GVV0, H9YVH7
      Conserved Domains (5) summary
      cd07934
      Location:38 → 221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:774 → 849
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      PHA03095
      Location:459 → 705
      PHA03095; ankyrin-like protein; Provisional
      cd01177
      Location:228 → 327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:599 → 630
      ANK; ANK repeat [structural motif]

    3. XM_015148076.2 → XP_015003562.2  nuclear factor NF-kappa-B p100 subunit isoform X3

      UniProtKB/TrEMBL
      A0A5S6R7A9, A0A8J8XDC2, F7GVU6, F7GVV0, G7N104
      Related
      ENSMMUP00000003998.4, ENSMMUT00000004238.4
      Conserved Domains (5) summary
      cd07934
      Location:38 → 221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:774 → 849
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      PHA03095
      Location:459 → 705
      PHA03095; ankyrin-like protein; Provisional
      cd01177
      Location:228 → 327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:599 → 630
      ANK; ANK repeat [structural motif]

    4. XM_015148075.2 → XP_015003561.2  nuclear factor NF-kappa-B p100 subunit isoform X2

      UniProtKB/TrEMBL
      F7GVV0
      Conserved Domains (5) summary
      cd08798
      Location:781 → 856
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      PHA03095
      Location:466 → 712
      PHA03095; ankyrin-like protein; Provisional
      cd01177
      Location:235 → 334
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:606 → 637
      ANK; ANK repeat [structural motif]
      cl08275
      Location:55 → 228
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)

    5. XM_015148074.2 → XP_015003560.2  nuclear factor NF-kappa-B p100 subunit isoform X1

      UniProtKB/TrEMBL
      F7GVV0
      Conserved Domains (5) summary
      cd08798
      Location:781 → 856
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      PHA03095
      Location:466 → 712
      PHA03095; ankyrin-like protein; Provisional
      cd01177
      Location:235 → 334
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:606 → 637
      ANK; ANK repeat [structural motif]
      cl08275
      Location:55 → 228
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
    Nucleotide Protein
    Heading Accession and Version

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