UBE3A ubiquitin protein ligase E3A [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: UBE3Aprovided by VGNC
Official Full Name: ubiquitin protein ligase E3Aprovided by VGNC
Primary source: VGNC:VGNC:99337
See related: Ensembl:ENSMMUG00000000628
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	7	NC_041760.1 (3572436..3671720)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	7	NC_027899.1 (2232185..2332636, complement)

Chromosome 7 - NC_041760.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

SHGC-52105 (e-PCR)
- UniSTS:17922

D21S1734E (e-PCR)
- UniSTS:150787

D15S837 (e-PCR)
- UniSTS:8208

WI-11918 (e-PCR)
- UniSTS:8209

D15S698E (e-PCR)
- UniSTS:151605

RH78150 (e-PCR)
- UniSTS:68662

G67875 (e-PCR)
- UniSTS:225595

RH45096 (e-PCR)
- UniSTS:347

RH17601 (e-PCR)
- UniSTS:77665

Ube3a (e-PCR), detects polymorphism
- UniSTS:275877

Ube3a (e-PCR), detects polymorphism
- UniSTS:275878

D15S122 (e-PCR)
- UniSTS:45255

D21S1716E (e-PCR)
- UniSTS:150773

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein polyubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ubiquitin-protein ligase E3A

NP_001247969.1

EC 6.3.2.19

XP_014997179.1

EC 6.3.2.19

XP_014997181.1

EC 6.3.2.19

XP_014997184.1

EC 6.3.2.19

XP_014997186.1

EC 6.3.2.19

XP_014997190.1

EC 6.3.2.19

XP_014997191.1

EC 6.3.2.19

XP_014997192.1

EC 6.3.2.19

XP_014997193.1

EC 6.3.2.19

XP_028706251.1

EC 6.3.2.19

XP_028706252.1

EC 6.3.2.19

XP_028706253.1

EC 6.3.2.19

XP_028706254.1

EC 6.3.2.19

XP_028706255.1

EC 6.3.2.19

XP_028706256.1

EC 6.3.2.19

XP_028706257.1

EC 6.3.2.19

XP_028706258.1

EC 6.3.2.19

XP_028706259.1

EC 6.3.2.19

XP_028706260.1

EC 6.3.2.19

XP_028706261.1

EC 6.3.2.19

XP_028706262.1

EC 6.3.2.19

XP_028706263.1

EC 6.3.2.19

XP_028706264.1

EC 6.3.2.19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261040.1 → NP_001247969.1 ubiquitin-protein ligase E3A

See identical proteins and their annotated locations for NP_001247969.1

Status: PROVISIONAL

Source sequence(s)

JV048146

UniProtKB/TrEMBL

A0A1D5QFU7, H9EMG4

Related

ENSMMUP00000018225.4, ENSMMUT00000019464.4

Conserved Domains (2) summary

cd00078
Location:520 → 870

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:26 → 80

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041760.1 Reference Mmul_10 Primary Assembly

Range

3572436..3671720

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015141693.2 → XP_014997179.1 ubiquitin-protein ligase E3A isoform X2

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 908

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850422.1 → XP_028706255.1 ubiquitin-protein ligase E3A isoform X2

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 908

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141704.2 → XP_014997190.1 ubiquitin-protein ligase E3A isoform X8

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 850

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141698.2 → XP_014997184.1 ubiquitin-protein ligase E3A isoform X6

UniProtKB/TrEMBL

G7MW72

Conserved Domains (2) summary

cd00078
Location:523 → 873

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:29 → 83

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141695.2 → XP_014997181.1 ubiquitin-protein ligase E3A isoform X2

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 908

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141705.2 → XP_014997191.1 ubiquitin-protein ligase E3A isoform X8

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 850

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141706.2 → XP_014997192.1 ubiquitin-protein ligase E3A isoform X8

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 850

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141707.2 → XP_014997193.1 ubiquitin-protein ligase E3A isoform X8

UniProtKB/TrEMBL

A0A1D5QFU7

Related

ENSMMUP00000059201.2, ENSMMUT00000053961.2

Conserved Domains (2) summary

cd00078
Location:500 → 850

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850418.1 → XP_028706251.1 ubiquitin-protein ligase E3A isoform X1

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 823

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850428.1 → XP_028706261.1 ubiquitin-protein ligase E3A isoform X5

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 765

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850424.1 → XP_028706257.1 ubiquitin-protein ligase E3A isoform X3

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:523 → 788

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:29 → 83

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850420.1 → XP_028706253.1 ubiquitin-protein ligase E3A isoform X1

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 823

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850429.1 → XP_028706262.1 ubiquitin-protein ligase E3A isoform X5

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 765

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850425.1 → XP_028706258.1 ubiquitin-protein ligase E3A isoform X4

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:520 → 785

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:26 → 80

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850430.1 → XP_028706263.1 ubiquitin-protein ligase E3A isoform X5

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 765

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850431.1 → XP_028706264.1 ubiquitin-protein ligase E3A isoform X5

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:500 → 765

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:6 → 60

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850421.1 → XP_028706254.1 ubiquitin-protein ligase E3A isoform X2

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 908

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_015141700.2 → XP_014997186.1 ubiquitin-protein ligase E3A isoform X7

UniProtKB/TrEMBL

A0A1D5QFU7, H9EMG4

Conserved Domains (2) summary

cd00078
Location:520 → 870

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:26 → 80

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850427.1 → XP_028706260.1 ubiquitin-protein ligase E3A isoform X4

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:520 → 785

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:26 → 80

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850423.1 → XP_028706256.1 ubiquitin-protein ligase E3A isoform X2

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 908

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850419.1 → XP_028706252.1 ubiquitin-protein ligase E3A isoform X1

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:558 → 823

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:64 → 118

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
XM_028850426.1 → XP_028706259.1 ubiquitin-protein ligase E3A isoform X4

UniProtKB/TrEMBL

A0A1D5QFU7

Conserved Domains (2) summary

cd00078
Location:520 → 785

HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

pfam16558
Location:26 → 80

AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A