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    MAP3K15 mitogen-activated protein kinase kinase kinase 15 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695958, updated on 5-Mar-2024

    Summary

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    Gene symbol
    MAP3K15
    Gene description
    mitogen-activated protein kinase kinase kinase 15
    See related
    Ensembl:ENSMMUG00000061236
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K15 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (19117620..19266474, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (18756739..18910052, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene phosphorylase kinase regulatory subunit alpha 2 Neighboring gene uncharacterized LOC106995167 Neighboring gene adhesion G protein-coupled receptor G2 Neighboring gene uncharacterized LOC114675068 Neighboring gene pyruvate dehydrogenase E1 subunit alpha 1 Neighboring gene uncharacterized LOC114674910 Neighboring gene SH3 domain containing kinase binding protein 1 Neighboring gene prothymosin alpha-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      19117620..19266474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127037.2 → XP_014982523.1  mitogen-activated protein kinase kinase kinase 15 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZMV6, A0A5F7ZNK0
      Related
      ENSMMUP00000066204.1, ENSMMUT00000099490.1
      Conserved Domains (3) summary
      cd06624
      Location:643 → 908
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:136 → 514
      DUF4071; Domain of unknown function (DUF4071)
      pfam19039
      Location:525 → 620
      ASK_PH; ASK kinase PH domain

    2. XM_028842438.1 → XP_028698271.1  mitogen-activated protein kinase kinase kinase 15 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AUN6
      Related
      ENSMMUP00000081199.1, ENSMMUT00000101932.1
      Conserved Domains (3) summary
      cd06624
      Location:635 → 900
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:136 → 506
      DUF4071; Domain of unknown function (DUF4071)
      pfam19039
      Location:517 → 612
      ASK_PH; ASK kinase PH domain

    RNA

    1. XR_003726166.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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