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    FOXO4 forkhead box O4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698055, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FOXO4provided by VGNC
    Official Full Name
    forkhead box O4provided by VGNC
    Primary source
    VGNC:VGNC:72712
    Locus tag
    EGK_20618
    See related
    Ensembl:ENSMMUG00000032429
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FOXO4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (68083007..68090731)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (65827087..65834563)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene suppressor of cytokine signaling 5-like Neighboring gene sorting nexin 12 Neighboring gene chromosome X CXorf65 homolog Neighboring gene interleukin 2 receptor subunit gamma Neighboring gene mediator complex subunit 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of FOXO1, 3 and 4 transcription factors in ovaries of fetal, prepubertal and adult rhesus macaques. Ting AY, et al. Biol Reprod, 2017 May 1. PMID 28444134, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in rhesus macaque ovaries of three developmental stages: fetal, prepubertal, and adult
      Title: Characterization of FOXO1, 3 and 4 transcription factors in ovaries of fetal, prepubertal and adult rhesus macaques.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    forkhead box protein O4
    Names
    Fork head domain transcription factor AFX1
    forkhead box protein O4-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      68083007..68090731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127651.2 → XP_014983137.1  forkhead box protein O4

      UniProtKB/TrEMBL
      A0A663DCA7, A0A8J8YSG8, F6UBP4, G7NRU9
      Related
      ENSMMUP00000040996.2, ENSMMUT00000047959.3
      Conserved Domains (4) summary
      pfam05887
      Location:4 → 82
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      cd00059
      Location:101 → 181
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16675
      Location:358 → 395
      FOXO_KIX_bdg; KIX-binding domain of forkhead box O, CR2
      pfam16676
      Location:465 → 503
      FOXO-TAD; Transactivation domain of FOXO protein family
    Nucleotide Protein
    Heading Accession and Version

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