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    MIA2 MIA SH3 domain ER export factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699511, updated on 5-Mar-2024

    Summary

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    Gene symbol
    MIA2
    Gene description
    MIA SH3 domain ER export factor 2
    See related
    Ensembl:ENSMMUG00000021121
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    CTAGE5
    Orthologs
    human mouse all
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    Genomic context

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    See MIA2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (101312003..101428126)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (100697659..100814553)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene pinin, desmosome associated protein Neighboring gene transmembrane protein 92 pseudogene Neighboring gene coilin pseudogene Neighboring gene 60S ribosomal protein L21 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle cargo loading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum exit site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    melanoma inhibitory activity protein 2
    Names
    CTAGE family member 5, ER export factor
    CTAGE family, member 5
    cutaneous T-cell lymphoma-associated antigen 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195820.1 → NP_001182749.1  melanoma inhibitory activity protein 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      CB230378, CN645258, CO645607, CO645657
      UniProtKB/TrEMBL
      F7DDF9
      Related
      ENSMMUP00000032954.3, ENSMMUT00000039894.3

    2. NM_001374449.1 → NP_001361378.1  melanoma inhibitory activity protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      QNVO02000421
      UniProtKB/TrEMBL
      F7DDH4
      Conserved Domains (2) summary
      cd11892
      Location:31 → 103
      SH3_MIA2; Src Homology 3 domain of Melanoma Inhibitory Activity 2 protein
      COG1196
      Location:698 → 1050
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      101312003..101428126
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015143541.2 → XP_014999027.2  melanoma inhibitory activity protein 2 isoform X2

      Related
      ENSMMUP00000032953.3, ENSMMUT00000039893.3
      Conserved Domains (2) summary
      cd11892
      Location:31 → 103
      SH3_MIA2; Src Homology 3 domain of Melanoma Inhibitory Activity 2 protein
      COG1196
      Location:698 → 1050
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_015143540.2 → XP_014999026.2  melanoma inhibitory activity protein 2 isoform X1

      Conserved Domains (2) summary
      cd11892
      Location:31 → 103
      SH3_MIA2; Src Homology 3 domain of Melanoma Inhibitory Activity 2 protein
      COG1196
      Location:782 → 1075
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    3. XM_015143543.2 → XP_014999029.2  melanoma inhibitory activity protein 2 isoform X4

      Conserved Domains (3) summary
      cd11892
      Location:31 → 103
      SH3_MIA2; Src Homology 3 domain of Melanoma Inhibitory Activity 2 protein
      COG1196
      Location:698 → 1050
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam03154
      Location:1146 → 1365
      Atrophin-1; Atrophin-1 family

    4. XM_015143542.2 → XP_014999028.2  melanoma inhibitory activity protein 2 isoform X3

      Conserved Domains (3) summary
      cd11892
      Location:31 → 103
      SH3_MIA2; Src Homology 3 domain of Melanoma Inhibitory Activity 2 protein
      COG1196
      Location:782 → 1075
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam03154
      Location:1155 → 1374
      Atrophin-1; Atrophin-1 family

    5. XM_015143549.2 → XP_014999035.2  melanoma inhibitory activity protein 2 isoform X10

      UniProtKB/TrEMBL
      F7DDF9, F7HDL2, I0FRU2
      Related
      ENSMMUP00000027809.4, ENSMMUT00000029713.4
      Conserved Domains (1) summary
      COG1196
      Location:78 → 430
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_028850258.1 → XP_028706091.1  melanoma inhibitory activity protein 2 isoform X15

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:78 → 430
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    7. XM_015143547.2 → XP_014999033.2  melanoma inhibitory activity protein 2 isoform X8

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:162 → 455
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    8. XM_015143554.2 → XP_014999040.2  melanoma inhibitory activity protein 2 isoform X16

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:61 → 413
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    9. XM_015143551.2 → XP_014999037.2  melanoma inhibitory activity protein 2 isoform X11

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:145 → 438
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    10. XM_015143552.2 → XP_014999038.2  melanoma inhibitory activity protein 2 isoform X12

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:61 → 413
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    11. XM_028850255.1 → XP_028706088.1  melanoma inhibitory activity protein 2 isoform X9

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:84 → 436
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    12. XM_015143545.2 → XP_014999031.2  melanoma inhibitory activity protein 2 isoform X6

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:168 → 461
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    13. XM_015143544.2 → XP_014999030.2  melanoma inhibitory activity protein 2 isoform X5

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:174 → 467
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    14. XM_015143546.2 → XP_014999032.2  melanoma inhibitory activity protein 2 isoform X7

      UniProtKB/TrEMBL
      F7DDD4, F7DDF9, H9FUK5
      Related
      ENSMMUP00000032956.3, ENSMMUT00000039895.3
      Conserved Domains (1) summary
      COG1196
      Location:90 → 442
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    15. XM_028850256.1 → XP_028706089.1  melanoma inhibitory activity protein 2 isoform X13

      UniProtKB/TrEMBL
      F7DDF9
      Conserved Domains (1) summary
      COG1196
      Location:174 → 467
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    16. XM_015143553.2 → XP_014999039.2  melanoma inhibitory activity protein 2 isoform X14

      UniProtKB/TrEMBL
      F7DDF9, F7HFK7, H9Z937
      Related
      ENSMMUP00000027804.4, ENSMMUT00000029708.4
      Conserved Domains (1) summary
      COG1196
      Location:90 → 442
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version

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