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    TSEN2 tRNA splicing endonuclease subunit 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695083, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TSEN2provided by VGNC
    Official Full Name
    tRNA splicing endonuclease subunit 2provided by VGNC
    Primary source
    VGNC:VGNC:82707
    See related
    Ensembl:ENSMMUG00000007195
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TSEN2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (143855667..143911488)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (53864799..53921179, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase Mu 5 pseudogene Neighboring gene peroxisome proliferator activated receptor gamma Neighboring gene 5S ribosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene MKRN2 opposite strand Neighboring gene makorin ring finger protein 2 Neighboring gene Raf-1 proto-oncogene, serine/threonine kinase Neighboring gene transmembrane protein 40

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tRNA-intron endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tRNA-type intron splice site recognition and cleavage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of tRNA-intron endonuclease complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA-splicing endonuclease subunit Sen2
    Names
    tRNA splicing endonuclease 2 homolog
    XP_014985699.2
    XP_014985700.2
    XP_014985701.2
    XP_028700302.1
    XP_028700303.1
    XP_028700305.1
    XP_028700306.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      143855667..143911488
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130213.2 → XP_014985699.2  tRNA-splicing endonuclease subunit Sen2 isoform X1

      UniProtKB/TrEMBL
      F7EQQ5, F7ER64, G7MKP7, H9G055, H9ZDW2
      Related
      ENSMMUP00000009442.4, ENSMMUT00000010058.4
      Conserved Domains (1) summary
      COG1676
      Location:297 → 425
      SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]

    2. XM_028844472.1 → XP_028700305.1  tRNA-splicing endonuclease subunit Sen2 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZP46, G7MKP7, H9ZDW2
      Conserved Domains (2) summary
      PRK09300
      Location:277 → 345
      PRK09300; tRNA splicing endonuclease; Reviewed
      pfam01974
      Location:313 → 396
      tRNA_int_endo; tRNA intron endonuclease, catalytic C-terminal domain

    3. XM_015130214.2 → XP_014985700.2  tRNA-splicing endonuclease subunit Sen2 isoform X1

      UniProtKB/TrEMBL
      F7EQQ5, F7ER64, G7MKP7, H9G055, H9ZDW2
      Related
      ENSMMUP00000009433.4, ENSMMUT00000010049.4
      Conserved Domains (1) summary
      COG1676
      Location:297 → 425
      SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]

    4. XM_028844473.1 → XP_028700306.1  tRNA-splicing endonuclease subunit Sen2 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZP46, G7MKP7, H9ZDW2
      Related
      ENSMMUP00000067389.1, ENSMMUT00000094015.1
      Conserved Domains (2) summary
      PRK09300
      Location:277 → 345
      PRK09300; tRNA splicing endonuclease; Reviewed
      pfam01974
      Location:313 → 396
      tRNA_int_endo; tRNA intron endonuclease, catalytic C-terminal domain

    5. XM_015130215.2 → XP_014985701.2  tRNA-splicing endonuclease subunit Sen2 isoform X1

      UniProtKB/TrEMBL
      F7EQQ5, F7ER64, G7MKP7, H9G055, H9ZDW2
      Related
      ENSMMUP00000078733.1, ENSMMUT00000104962.1
      Conserved Domains (1) summary
      COG1676
      Location:297 → 425
      SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]

    6. XM_028844470.1 → XP_028700303.1  tRNA-splicing endonuclease subunit Sen2 isoform X1

      UniProtKB/TrEMBL
      F7EQQ5, F7ER64, G7MKP7, H9G055, H9ZDW2
      Conserved Domains (1) summary
      COG1676
      Location:297 → 425
      SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]

    7. XM_028844469.1 → XP_028700302.1  tRNA-splicing endonuclease subunit Sen2 isoform X1

      UniProtKB/TrEMBL
      F7EQQ5, F7ER64, G7MKP7, H9G055, H9ZDW2
      Conserved Domains (1) summary
      COG1676
      Location:297 → 425
      SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]

    RNA

    1. XR_003727402.1 RNA Sequence

    2. XR_003727401.1 RNA Sequence

    3. XR_003727403.1 RNA Sequence

    4. XR_003727405.1 RNA Sequence

    5. XR_003727404.1 RNA Sequence

    6. XR_003727408.1 RNA Sequence

    7. XR_003727410.1 RNA Sequence

    8. XR_003727409.1 RNA Sequence

    9. XR_003727411.1 RNA Sequence

    10. XR_003727406.1 RNA Sequence

    11. XR_003727407.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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