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    L2HGDH L-2-hydroxyglutarate dehydrogenase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705721, updated on 17-Aug-2024

    Summary

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    Official Symbol
    L2HGDHprovided by VGNC
    Official Full Name
    L-2-hydroxyglutarate dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:74090
    Locus tag
    EGK_18174
    See related
    Ensembl:ENSMMUG00000007468
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See L2HGDH in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (112450434..112521560, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (112253695..112324258, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene valosin containing protein lysine methyltransferase Neighboring gene SOS Ras/Rho guanine nucleotide exchange factor 2 Neighboring gene 28S ribosomal protein S5, mitochondrial pseudogene Neighboring gene distal membrane arm assembly component 2 like Neighboring gene cyclin dependent kinase like 1 Neighboring gene uncharacterized LOC106999425

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables (S)-2-hydroxy-acid oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 2-hydroxyglutarate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    L-2-hydroxyglutarate dehydrogenase, mitochondrial
    XP_001099959.1
    XP_014999144.1
    XP_028707370.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      112450434..112521560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001099959.4 → XP_001099959.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_001099959.1

      UniProtKB/TrEMBL
      A0A5S6R7L4, A0A8J8XXA7, F6SVW9, F6SVX9, G7MXQ7
      Related
      ENSMMUP00000009796.4, ENSMMUT00000010438.4
      Conserved Domains (1) summary
      PRK11728
      Location:61 → 457
      PRK11728; hydroxyglutarate oxidase; Provisional

    2. XM_028851537.1 → XP_028707370.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A5S6R7L4, A0A8J8XXA7, F6SVW9, F6SVX9, G7MXQ7
      Conserved Domains (1) summary
      PRK11728
      Location:61 → 457
      PRK11728; hydroxyglutarate oxidase; Provisional

    3. XM_015143658.2 → XP_014999144.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      F6SVW9
      Conserved Domains (1) summary
      PRK11728
      Location:25 → 421
      PRK11728; L-2-hydroxyglutarate oxidase
    Nucleotide Protein
    Heading Accession and Version

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