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    SORL1 sortilin related receptor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713011, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SORL1provided by VGNC
    Official Full Name
    sortilin related receptor 1provided by VGNC
    Primary source
    VGNC:VGNC:101401
    See related
    Ensembl:ENSMMUG00000014880
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SORL1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    51
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (114500162..114680468)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (114324759..114504242)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene tubulin folding cofactor E like Neighboring gene tectorin alpha Neighboring gene sterol-C5-desaturase Neighboring gene chromosome transmission fidelity protein 8 homolog Neighboring gene COX assembly mitochondrial protein homolog Neighboring gene uncharacterized LOC106993508 Neighboring gene microRNA mir-125b-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in post-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein retention in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein targeting to lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sortilin-related receptor
    Names
    sortilin-related receptor preproprotein
    sortilin-related receptor, L(DLR class) A repeats-containing

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      114500162..114680468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834091.1 → XP_028689924.1  sortilin-related receptor isoform X2

      UniProtKB/TrEMBL
      A0A1D5R9V4
      Conserved Domains (8) summary
      smart00192
      Location:1094 → 1126
      LDLa; Low-density lipoprotein receptor domain class A
      smart00060
      Location:1645 → 1725
      FN3; Fibronectin type 3 domain
      smart00135
      Location:720 → 762
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00602
      Location:20 → 649
      VPS10; VPS10 domain
      cd00063
      Location:1547 → 1638
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00112
      Location:1221 → 1255
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00058
      Location:786 → 825
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      pfam00057
      Location:1053 → 1088
      Ldl_recept_a; Low-density lipoprotein receptor domain class A

    2. XM_015115975.2 → XP_014971461.2  sortilin-related receptor isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0E5, H9ZCQ1
      Related
      ENSMMUP00000053778.2, ENSMMUT00000064203.2
      Conserved Domains (8) summary
      smart00192
      Location:1198 → 1230
      LDLa; Low-density lipoprotein receptor domain class A
      smart00060
      Location:1749 → 1829
      FN3; Fibronectin type 3 domain
      smart00135
      Location:824 → 866
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00602
      Location:124 → 753
      VPS10; VPS10 domain
      cd00063
      Location:1651 → 1742
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00112
      Location:1325 → 1359
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00058
      Location:890 → 929
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      pfam00057
      Location:1157 → 1192
      Ldl_recept_a; Low-density lipoprotein receptor domain class A

    3. XM_028834092.1 → XP_028689925.1  sortilin-related receptor isoform X2

      UniProtKB/TrEMBL
      A0A1D5R9V4
      Conserved Domains (8) summary
      smart00192
      Location:1094 → 1126
      LDLa; Low-density lipoprotein receptor domain class A
      smart00060
      Location:1645 → 1725
      FN3; Fibronectin type 3 domain
      smart00135
      Location:720 → 762
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00602
      Location:20 → 649
      VPS10; VPS10 domain
      cd00063
      Location:1547 → 1638
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00112
      Location:1221 → 1255
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00058
      Location:786 → 825
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      pfam00057
      Location:1053 → 1088
      Ldl_recept_a; Low-density lipoprotein receptor domain class A

    4. XM_028834093.1 → XP_028689926.1  sortilin-related receptor isoform X2

      UniProtKB/TrEMBL
      A0A1D5R9V4
      Related
      ENSMMUP00000057095.2, ENSMMUT00000058098.2
      Conserved Domains (8) summary
      smart00192
      Location:1094 → 1126
      LDLa; Low-density lipoprotein receptor domain class A
      smart00060
      Location:1645 → 1725
      FN3; Fibronectin type 3 domain
      smart00135
      Location:720 → 762
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00602
      Location:20 → 649
      VPS10; VPS10 domain
      cd00063
      Location:1547 → 1638
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00112
      Location:1221 → 1255
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00058
      Location:786 → 825
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      pfam00057
      Location:1053 → 1088
      Ldl_recept_a; Low-density lipoprotein receptor domain class A
    Nucleotide Protein
    Heading Accession and Version

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