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    GRK6 G protein-coupled receptor kinase 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700000, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRK6provided by VGNC
    Official Full Name
    G protein-coupled receptor kinase 6provided by VGNC
    Primary source
    VGNC:VGNC:73268
    See related
    Ensembl:ENSMMUG00000019817
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GRK6 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (174917708..174934948)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (176081445..176098684)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene profilin 3 Neighboring gene coagulation factor XII Neighboring gene proline rich 7, synaptic Neighboring gene drebrin 1 Neighboring gene uncharacterized LOC114678984 Neighboring gene PDZ and LIM domain 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G protein-coupled receptor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G protein-coupled receptor kinase 6
    XP_014997001.1
    XP_014997003.1
    XP_014997004.1
    XP_028705786.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      174917708..174934948
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141515.2 → XP_014997001.1  G protein-coupled receptor kinase 6 isoform X1

      UniProtKB/TrEMBL
      H9F8Z1
      Related
      ENSMMUP00000071408.1, ENSMMUT00000097113.1
      Conserved Domains (2) summary
      cd05630
      Location:185 → 469
      STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
      cl02565
      Location:35 → 179
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    2. XM_015141517.2 → XP_014997003.1  G protein-coupled receptor kinase 6 isoform X2

      UniProtKB/TrEMBL
      A0A5F8A9L1, H9F8Z1
      Related
      ENSMMUP00000073651.1, ENSMMUT00000092920.1
      Conserved Domains (2) summary
      cd05630
      Location:185 → 469
      STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
      cl02565
      Location:35 → 179
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    3. XM_028849953.1 → XP_028705786.1  G protein-coupled receptor kinase 6 isoform X4

      UniProtKB/TrEMBL
      G7MUG2
      Conserved Domains (2) summary
      cd05630
      Location:80 → 364
      STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
      cl02565
      Location:1 → 74
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    4. XM_015141518.2 → XP_014997004.1  G protein-coupled receptor kinase 6 isoform X3

      UniProtKB/TrEMBL
      G7MUG2
      Conserved Domains (3) summary
      smart00220
      Location:156 → 418
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05630
      Location:155 → 439
      STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
      cl02565
      Location:20 → 149
      RGS; Regulator of G protein signaling (RGS) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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