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    MEF2A myocyte enhancer factor 2A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708956, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MEF2Aprovided by VGNC
    Official Full Name
    myocyte enhancer factor 2Aprovided by VGNC
    Primary source
    VGNC:VGNC:74698
    See related
    Ensembl:ENSMMUG00000018122
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MEF2A in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (78767335..78928601)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (78225780..78386855)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene endoplasmin-like Neighboring gene leucine rich repeat containing 28 Neighboring gene uncharacterized LOC114679268 Neighboring gene LysM domain containing 4 Neighboring gene golgin subfamily A member 8S-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myocyte-specific enhancer factor 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260914.1 → NP_001247843.1  myocyte-specific enhancer factor 2A

      See identical proteins and their annotated locations for NP_001247843.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047086
      UniProtKB/TrEMBL
      H9FUJ3
      Related
      ENSMMUP00000023816.4, ENSMMUT00000025457.4
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      78767335..78928601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028850378.1 → XP_028706211.1  myocyte-specific enhancer factor 2A isoform X6

      Conserved Domains (2) summary
      pfam12347
      Location:29 → 88
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
      cl00109
      Location:2 → 18
      MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...

    2. XM_015143130.2 → XP_014998616.1  myocyte-specific enhancer factor 2A isoform X1

      UniProtKB/TrEMBL
      A0A1D5R1Y7
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 156
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    3. XM_015143134.2 → XP_014998620.1  myocyte-specific enhancer factor 2A isoform X2

      UniProtKB/TrEMBL
      H9FUJ5
      Conserved Domains (3) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam11597
      Location:129 → 238
      Med13_N; Mediator complex subunit 13 N-terminal
      pfam12347
      Location:98 → 152
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    4. XM_015143137.2 → XP_014998623.1  myocyte-specific enhancer factor 2A isoform X5

      UniProtKB/TrEMBL
      A0A1D5R1Y7, F7FGA1, H9FUJ6
      Related
      ENSMMUP00000054321.2, ENSMMUT00000079107.2
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    5. XM_028850379.1 → XP_028706212.1  myocyte-specific enhancer factor 2A isoform X7

      Conserved Domains (2) summary
      pfam12347
      Location:29 → 82
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
      cl00109
      Location:2 → 25
      MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...

    6. XM_028850380.1 → XP_028706213.1  myocyte-specific enhancer factor 2A isoform X8

      Conserved Domains (2) summary
      pfam12347
      Location:29 → 82
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
      cl00109
      Location:2 → 25
      MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...

    7. XM_015143136.2 → XP_014998622.1  myocyte-specific enhancer factor 2A isoform X4

      UniProtKB/TrEMBL
      F7FGB3
      Related
      ENSMMUP00000023814.2, ENSMMUT00000025455.4
      Conserved Domains (3) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam11597
      Location:129 → 238
      Med13_N; Mediator complex subunit 13 N-terminal
      pfam12347
      Location:98 → 152
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    8. XM_015143135.2 → XP_014998621.1  myocyte-specific enhancer factor 2A isoform X3

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:98 → 156
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    9. XM_028850376.1 → XP_028706209.1  myocyte-specific enhancer factor 2A isoform X1

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 156
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    10. XM_015143131.2 → XP_014998617.1  myocyte-specific enhancer factor 2A isoform X1

      UniProtKB/TrEMBL
      A0A1D5R1Y7
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 156
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    11. XM_028850377.1 → XP_028706210.1  myocyte-specific enhancer factor 2A isoform X1

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 156
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    Nucleotide Protein
    Heading Accession and Version

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