U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    LATS1 large tumor suppressor kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696131, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    LATS1provided by VGNC
    Official Full Name
    large tumor suppressor kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:74238
    See related
    Ensembl:ENSMMUG00000009827
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LATS1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (55630858..55688865, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (116767114..116825248)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene katanin catalytic subunit A1 Neighboring gene uncharacterized LOC106998078 Neighboring gene nucleoporin 43 Neighboring gene protein-L-isoaspartate (D-aspartate) O-methyltransferase Neighboring gene BTB/POZ domain-containing protein 10 pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein kinase LATS1
    Names
    serine/threonine-protein kinase LATS1-like

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      55630858..55688865 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002808396.3 → XP_002808442.3  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AEZ3, A0A8J8Y1Z6, G7MQ56, H9G1M9
      Related
      ENSMMUP00000072200.1, ENSMMUT00000084294.1
      Conserved Domains (4) summary
      PRK10263
      Location:467 → 655
      PRK10263; DNA translocase FtsK; Provisional
      PRK14950
      Location:473 → 558
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      cd14397
      Location:103 → 143
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:703 → 1084
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    2. XM_015137141.2 → XP_014992627.1  serine/threonine-protein kinase LATS1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AQ42
      Related
      ENSMMUP00000080059.1, ENSMMUT00000087125.1
      Conserved Domains (3) summary
      smart00220
      Location:588 → 893
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05625
      Location:586 → 967
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1
      cl21463
      Location:1 → 26
      UBA_like_SF; UBA domain-like superfamily

    3. XM_028847199.1 → XP_028703032.1  serine/threonine-protein kinase LATS1 isoform X4

      Conserved Domains (4) summary
      PHA03247
      Location:9 → 312
      PHA03247; large tegument protein UL36; Provisional
      PRK10263
      Location:187 → 375
      PRK10263; DNA translocase FtsK; Provisional
      PRK14950
      Location:193 → 278
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      cd05625
      Location:423 → 804
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    4. XM_028847198.1 → XP_028703031.1  serine/threonine-protein kinase LATS1 isoform X3

      UniProtKB/TrEMBL
      F6WYK6
      Related
      ENSMMUP00000012865.4, ENSMMUT00000013730.4
      Conserved Domains (5) summary
      PHA03247
      Location:289 → 592
      PHA03247; large tegument protein UL36; Provisional
      PRK10263
      Location:467 → 655
      PRK10263; DNA translocase FtsK; Provisional
      PRK14950
      Location:473 → 558
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      cd14397
      Location:103 → 143
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cl21453
      Location:703 → 964
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials