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    TFPI2 tissue factor pathway inhibitor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700850, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFPI2provided by VGNC
    Official Full Name
    tissue factor pathway inhibitor 2provided by VGNC
    Primary source
    VGNC:VGNC:78329
    Locus tag
    EGK_13934
    See related
    Ensembl:ENSMMUG00000020581
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TFPI2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (112232134..112264654)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (119252757..119257744, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene G protein subunit gamma 11 Neighboring gene G protein subunit gamma transducin 1 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 pseudogene Neighboring gene uncharacterized LOC106997559

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tissue factor pathway inhibitor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      112232134..112264654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846058.1 → XP_028701891.1  tissue factor pathway inhibitor 2 isoform X2

      Conserved Domains (2) summary
      cd00109
      Location:88 → 140
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam00014
      Location:211 → 262
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

    2. XM_001099023.4 → XP_001099023.2  tissue factor pathway inhibitor 2 isoform X1

      UniProtKB/TrEMBL
      F7CWN2, G7MLV9
      Related
      ENSMMUP00000027091.3, ENSMMUT00000028952.4
      Conserved Domains (2) summary
      cd00109
      Location:88 → 140
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam00014
      Location:211 → 262
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

    RNA

    1. XR_003728264.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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