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    IQSEC1 IQ motif and Sec7 domain ArfGEF 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693922, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IQSEC1provided by VGNC
    Official Full Name
    IQ motif and Sec7 domain ArfGEF 1provided by VGNC
    Primary source
    VGNC:VGNC:73677
    Locus tag
    EGK_11404
    See related
    Ensembl:ENSMMUG00000001342
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IQSEC1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (144285735..144677382, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (53118903..53511388)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA7 Neighboring gene intraflagellar transport protein 122 homolog Neighboring gene ribosomal protein L32 Neighboring gene nucleoporin 210 Neighboring gene proline-rich protein 3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    IQ motif and SEC7 domain-containing protein 1
    Names
    IQ motif and Sec7 domain 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261803.1 → NP_001248732.1  IQ motif and SEC7 domain-containing protein 1

      See identical proteins and their annotated locations for NP_001248732.1

      Status: PROVISIONAL

      Source sequence(s)
      JU337386
      UniProtKB/TrEMBL
      A0A1D5Q9H8, F7B954, H9G2M8
      Related
      ENSMMUP00000044696.2, ENSMMUT00000078939.2
      Conserved Domains (2) summary
      cd13318
      Location:735 → 865
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:510 → 698
      Sec7; Sec7 domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      144285735..144677382 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843082.1 → XP_028698915.1  IQ motif and SEC7 domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A5F8AML9
      Conserved Domains (2) summary
      cd13318
      Location:845 → 975
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:620 → 808
      Sec7; Sec7 domain

    2. XM_028843083.1 → XP_028698916.1  IQ motif and SEC7 domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      F7B961
      Conserved Domains (2) summary
      cd13318
      Location:845 → 975
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:620 → 808
      Sec7; Sec7 domain

    3. XM_015130119.2 → XP_014985605.2  IQ motif and SEC7 domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZE49, F7B954
      Related
      ENSMMUP00000063862.1, ENSMMUT00000109710.1
      Conserved Domains (2) summary
      pfam01369
      Location:620 → 808
      Sec7; Sec7 domain
      pfam16453
      Location:840 → 975
      IQ_SEC7_PH; PH domain

    4. XM_015130123.2 → XP_014985609.1  IQ motif and SEC7 domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      F7B961, G7MKP0
      Related
      ENSMMUP00000078210.1, ENSMMUT00000094942.1
      Conserved Domains (2) summary
      pfam01369
      Location:524 → 712
      Sec7; Sec7 domain
      pfam16453
      Location:744 → 879
      IQ_SEC7_PH; PH domain

    5. XM_028843084.1 → XP_028698917.1  IQ motif and SEC7 domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      F7B961
      Conserved Domains (2) summary
      cd13318
      Location:845 → 975
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:620 → 808
      Sec7; Sec7 domain

    6. XM_015130116.2 → XP_014985602.1  IQ motif and SEC7 domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZA09, F7B954
      Related
      ENSMMUP00000062395.1, ENSMMUT00000098571.1
      Conserved Domains (2) summary
      cd13318
      Location:750 → 880
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:525 → 713
      Sec7; Sec7 domain

    7. XM_028843081.1 → XP_028698914.1  IQ motif and SEC7 domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AS01, F7B954
      Conserved Domains (2) summary
      pfam01369
      Location:402 → 590
      Sec7; Sec7 domain
      pfam16453
      Location:622 → 757
      IQ_SEC7_PH; PH domain

    8. XM_015130117.2 → XP_014985603.1  IQ motif and SEC7 domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      F7B954
      Related
      ENSMMUP00000067748.1, ENSMMUT00000104374.1
      Conserved Domains (2) summary
      cd13318
      Location:750 → 880
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:525 → 713
      Sec7; Sec7 domain

    9. XM_028843085.1 → XP_028698918.1  IQ motif and SEC7 domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AS01, F7B954
      Related
      ENSMMUP00000079680.1, ENSMMUT00000091889.1
      Conserved Domains (2) summary
      pfam01369
      Location:402 → 590
      Sec7; Sec7 domain
      pfam16453
      Location:622 → 757
      IQ_SEC7_PH; PH domain

    10. XM_015130118.2 → XP_014985604.1  IQ motif and SEC7 domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A5F7Z7Z5, F7B954
      Related
      ENSMMUP00000061225.1, ENSMMUT00000104338.1
      Conserved Domains (2) summary
      cd13318
      Location:749 → 879
      PH_IQSEC; IQ motif and SEC7 domain-containing protein family Pleckstrin homology domain
      pfam01369
      Location:524 → 712
      Sec7; Sec7 domain
    Nucleotide Protein
    Heading Accession and Version

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