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    CD28 CD28 molecule [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705313, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CD28provided by VGNC
    Official Full Name
    CD28 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:70759
    Locus tag
    EGK_04709
    See related
    Ensembl:ENSMMUG00000057214
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CD28 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (91104946..91138544)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (85399359..85432374)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene BUB3-interacting and GLEBS motif-containing protein ZNF207-like Neighboring gene cytochrome c oxidase subunit NDUFA4 pseudogene Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene nucleophosmin-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules. Villinger F, et al. Immunogenetics, 2001 May-Jun. PMID 11491535
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in T cell costimulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-cell-specific surface glycoprotein CD28
    Names
    CD28 precursor protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042641.2 → NP_001036106.2  T-cell-specific surface glycoprotein CD28 precursor

      See identical proteins and their annotated locations for NP_001036106.2

      Status: PROVISIONAL

      Source sequence(s)
      DQ872187
      UniProtKB/TrEMBL
      F7CGP5, Q0PDN4, Q9BDM6
      Related
      ENSMMUP00000065245.1, ENSMMUT00000103996.1
      Conserved Domains (1) summary
      cd05721
      Location:21 → 136
      IgV_CTLA-4; Immunoglobulin (Ig) domain of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      91104946..91138544
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110721.2 → XP_014966207.1  T-cell-specific surface glycoprotein CD28 isoform X1

      UniProtKB/TrEMBL
      G7N8Q2, Q9BDM6
      Conserved Domains (1) summary
      cd05721
      Location:35 → 150
      IgV_CTLA-4; Immunoglobulin (Ig) domain of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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