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    ST14 ST14 transmembrane serine protease matriptase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718848, updated on 17-Aug-2024

    Summary

    Official Symbol
    ST14provided by VGNC
    Official Full Name
    ST14 transmembrane serine protease matriptaseprovided by VGNC
    Primary source
    VGNC:VGNC:77897
    See related
    Ensembl:ENSMMUG00000018034
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See ST14 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (122819033..122871541)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (122874020..122925372)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)-like Neighboring gene amyloid beta precursor like protein 2 Neighboring gene U4 spliceosomal RNA Neighboring gene zinc finger and BTB domain containing 44 Neighboring gene small nucleolar RNA U3 Neighboring gene ATP-dependent RNA helicase DDX18-like

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in acrosome reaction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    suppressor of tumorigenicity 14 protein
    Names
    suppression of tumorigenicity 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      122819033..122871541
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015116118.2XP_014971604.2  suppressor of tumorigenicity 14 protein isoform X2

      UniProtKB/TrEMBL
      H9ZCT3
      Related
      ENSMMUP00000023696.4, ENSMMUT00000025330.4
      Conserved Domains (4) summary
      cd00041
      Location:340444
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:525559
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd00190
      Location:615852
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam01390
      Location:88176
      SEA; SEA domain
    2. XM_015116117.2XP_014971603.2  suppressor of tumorigenicity 14 protein isoform X1

      UniProtKB/TrEMBL
      H9ZCT3
      Conserved Domains (4) summary
      cd00041
      Location:341445
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:526560
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd00190
      Location:616853
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam01390
      Location:89177
      SEA; SEA domain