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SOX6 SRY-box transcription factor 6 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 697831, updated on 17-Aug-2024

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Summary

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Official Symbol: SOX6provided by VGNC
Official Full Name: SRY-box transcription factor 6provided by VGNC
Primary source: VGNC:VGNC:77931
See related: Ensembl:ENSMMUG00000002753
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

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See SOX6 in Genome Data Viewer

Location:: chromosome: 14

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (49011566..49673718)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	14	NC_027906.1 (49821379..50481887)

Chromosome 14 - NC_041767.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SOX6_844 (e-PCR)
- UniSTS:277764

G63381 (e-PCR)
- UniSTS:140345

RH65285 (e-PCR)
- UniSTS:46963

WI-16902 (e-PCR)
- UniSTS:19635

RH68714 (e-PCR)
- UniSTS:28347

WI-17844 (e-PCR)
- UniSTS:52420

STS-H69535 (e-PCR)
- UniSTS:62663

SHGC-83953 (e-PCR)
- UniSTS:103624

SHGC-83873 (e-PCR)
- UniSTS:101843

SHGC-83438 (e-PCR)
- UniSTS:182495

D11S2872 (e-PCR)
- UniSTS:152050

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell fate commitment	IEA Inferred from Electronic Annotation more info	PubMed
involved_in central nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of chondrocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transcription factor SOX-6

Names: SRY (sex determining region Y)-box 6; SRY-box 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041767.1 Reference Mmul_10 Primary Assembly

Range

49011566..49673718

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015114803.2 → XP_014970289.1 transcription factor SOX-6 isoform X16

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:600 → 671

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_015114789.2 → XP_014970275.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114788.2 → XP_014970274.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028833622.1 → XP_028689455.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114793.2 → XP_014970279.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028833619.1 → XP_028689452.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028833623.1 → XP_028689456.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028833621.1 → XP_028689454.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028833620.1 → XP_028689453.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Related

ENSMMUP00000003700.3, ENSMMUT00000003916.4

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114786.2 → XP_014970272.1 transcription factor SOX-6 isoform X7

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:638 → 709

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_001090887.4 → XP_001090887.1 transcription factor SOX-6 isoform X18

See identical proteins and their annotated locations for XP_001090887.1

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:596 → 667

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114794.2 → XP_014970280.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114792.2 → XP_014970278.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114795.2 → XP_014970281.1 transcription factor SOX-6 isoform X8

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:635 → 706

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114784.2 → XP_014970270.1 transcription factor SOX-6 isoform X5

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:647 → 718

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_028833626.1 → XP_028689459.1 transcription factor SOX-6 isoform X19

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:628 → 699

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114785.2 → XP_014970271.1 transcription factor SOX-6 isoform X6

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:642 → 713

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_015114780.2 → XP_014970266.1 transcription factor SOX-6 isoform X1

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:662 → 733

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_028833618.1 → XP_028689451.1 transcription factor SOX-6 isoform X3

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:661 → 732

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114781.2 → XP_014970267.1 transcription factor SOX-6 isoform X2

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:661 → 732

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_015114797.2 → XP_014970283.1 transcription factor SOX-6 isoform X9

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:627 → 698

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_015114783.2 → XP_014970269.1 transcription factor SOX-6 isoform X4

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:648 → 719

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_028833624.1 → XP_028689457.1 transcription factor SOX-6 isoform X12

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:620 → 691

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114799.2 → XP_014970285.1 transcription factor SOX-6 isoform X11

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:620 → 691

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_015114801.2 → XP_014970287.1 transcription factor SOX-6 isoform X14

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:606 → 677

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114798.2 → XP_014970284.1 transcription factor SOX-6 isoform X10

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:621 → 692

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_015114800.2 → XP_014970286.1 transcription factor SOX-6 isoform X13

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:607 → 678

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114802.2 → XP_014970288.1 transcription factor SOX-6 isoform X17

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:600 → 671

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
XM_028833625.1 → XP_028689458.1 transcription factor SOX-6 isoform X15

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:605 → 676

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015114804.2 → XP_014970290.1 transcription factor SOX-6 isoform X20

UniProtKB/TrEMBL

F7H4A5

Conserved Domains (1) summary

cd01388
Location:524 → 595

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028833627.1 → XP_028689460.1 transcription factor SOX-6 isoform X21

Conserved Domains (1) summary

cd01388
Location:459 → 530

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...