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    FLNA filamin A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699524, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FLNAprovided by VGNC
    Official Full Name
    filamin Aprovided by VGNC
    Primary source
    VGNC:VGNC:72671
    See related
    Ensembl:ENSMMUG00000013668
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FLNA in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (150281800..150308021)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (147730824..147757036)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene emerin Neighboring gene translation initiation factor IF-2-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene ribosomal protein L10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    filamin-A
    Names
    filamin A, alpha (actin binding protein 280)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      150281800..150308021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001091203.3 → XP_001091203.3  filamin-A isoform X2

      UniProtKB/TrEMBL
      H9YVB1, I2CYJ1
      Related
      ENSMMUP00000017981.4, ENSMMUT00000019199.4
      Conserved Domains (4) summary
      smart00033
      Location:172 → 264
      CH; Calponin homology domain
      smart00557
      Location:1448 → 1542
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:44 → 148
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00630
      Location:1445 → 1536
      Filamin; Filamin/ABP280 repeat

    2. XM_001091073.3 → XP_001091073.2  filamin-A isoform X1

      UniProtKB/TrEMBL
      F7GCM2, H9FRS8, I2CYJ2
      Related
      ENSMMUP00000017986.3, ENSMMUT00000019204.4
      Conserved Domains (3) summary
      smart00557
      Location:1448 → 1542
      IG_FLMN; Filamin-type immunoglobulin domains
      cd21308
      Location:25 → 153
      CH_FLNA_rpt1; first calponin homology (CH) domain found in filamin-A (FLN-A) and similar proteins
      cd21312
      Location:156 → 269
      CH_FLNA_rpt2; second calponin homology (CH) domain found in filamin-A (FLN-A) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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