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    PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702929, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PIK3C2Gprovided by VGNC
    Official Full Name
    phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gammaprovided by VGNC
    Primary source
    VGNC:VGNC:75993
    See related
    Ensembl:ENSMMUG00000022174
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PIK3C2G in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (19637002..20060389)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (19114466..19518928)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000786 Neighboring gene uncharacterized LOC114670802 Neighboring gene dnaJ homolog subfamily C member 8 pseudogene Neighboring gene zinc finger CCHC domain-containing protein 9 pseudogene Neighboring gene uncharacterized LOC107000787 Neighboring gene phospholipase C zeta 1 Neighboring gene capping actin protein of muscle Z-line subunit alpha 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      19637002..20060389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028829284.1 → XP_028685117.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHC7, F6XHZ4
      Related
      ENSMMUP00000072789.1, ENSMMUT00000089811.1
      Conserved Domains (6) summary
      cd04012
      Location:520 → 678
      C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
      cd00869
      Location:692 → 860
      PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
      cd05177
      Location:867 → 1219
      PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
      cl02484
      Location:279 → 367
      PI3K_rbd; PI3-kinase family, ras-binding domain
      cl02563
      Location:1249 → 1348
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
      cl14603
      Location:1370 → 1482
      C2; C2 domain

    2. XM_028829283.1 → XP_028685116.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHC7, F6XHZ4
      Related
      ENSMMUP00000065033.1, ENSMMUT00000109885.1
      Conserved Domains (6) summary
      cd04012
      Location:520 → 678
      C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
      cd00869
      Location:692 → 860
      PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
      cd05177
      Location:867 → 1219
      PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
      cl02484
      Location:279 → 367
      PI3K_rbd; PI3-kinase family, ras-binding domain
      cl02563
      Location:1249 → 1348
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
      cl14603
      Location:1370 → 1482
      C2; C2 domain

    3. XM_028829285.1 → XP_028685118.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X2

      UniProtKB/TrEMBL
      F6XHZ4
      Conserved Domains (6) summary
      cd06896
      Location:1027 → 1126
      PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
      cd04012
      Location:298 → 456
      C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
      cd00869
      Location:470 → 638
      PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
      cd05177
      Location:645 → 997
      PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
      cl02484
      Location:57 → 145
      PI3K_rbd; PI3-kinase family, ras-binding domain
      cl14603
      Location:1148 → 1260
      C2; C2 domain

    4. XM_015151210.2 → XP_015006696.2  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHC7, F6XHZ4
      Conserved Domains (6) summary
      cd04012
      Location:520 → 678
      C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
      cd00869
      Location:692 → 860
      PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
      cd05177
      Location:867 → 1219
      PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
      cl02484
      Location:279 → 367
      PI3K_rbd; PI3-kinase family, ras-binding domain
      cl02563
      Location:1249 → 1348
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
      cl14603
      Location:1370 → 1482
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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