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    DFFA DNA fragmentation factor subunit alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713544, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DFFAprovided by VGNC
    Official Full Name
    DNA fragmentation factor subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:71771
    See related
    Ensembl:ENSMMUG00000032254
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DFFA in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (213993572..214032965)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (9704249..9716631, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114674150 Neighboring gene uncharacterized LOC114674148 Neighboring gene peroxisomal biogenesis factor 14 Neighboring gene centromere protein S Neighboring gene cortistatin Neighboring gene phosphogluconate dehydrogenase Neighboring gene kinesin family member 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables deoxyribonuclease inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic DNA fragmentation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA fragmentation factor subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260683.1 → NP_001247612.1  DNA fragmentation factor subunit alpha

      See identical proteins and their annotated locations for NP_001247612.1

      Status: PROVISIONAL

      Source sequence(s)
      JU474525
      UniProtKB/TrEMBL
      F7HGW2
      Related
      ENSMMUP00000015307.2, ENSMMUT00000016337.4
      Conserved Domains (2) summary
      pfam09033
      Location:100 → 264
      DFF-C; DNA Fragmentation factor 45kDa, C terminal domain
      cl02541
      Location:18 → 96
      CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      213993572..214032965
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028844810.1 → XP_028700643.1  DNA fragmentation factor subunit alpha isoform X1

      UniProtKB/TrEMBL
      H9Z5W4
      Related
      ENSMMUP00000076760.1, ENSMMUT00000103074.1
      Conserved Domains (2) summary
      pfam09033
      Location:100 → 261
      DFF-C; DNA Fragmentation factor 45kDa, C terminal domain
      cl02541
      Location:18 → 96
      CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...

    RNA

    1. XR_003727720.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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