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    CLEC7A C-type lectin domain containing 7A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574356, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CLEC7Aprovided by VGNC
    Official Full Name
    C-type lectin domain containing 7Aprovided by VGNC
    Primary source
    VGNC:VGNC:97753
    See related
    Ensembl:ENSMMUG00000002192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CLEC7A in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (9579997..9592761)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (10470055..10482812, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 52B Neighboring gene uncharacterized LOC107000757 Neighboring gene oxidized low density lipoprotein receptor 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A/B-like Neighboring gene C-type lectin domain family 1 member A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Simian immunodeficiency virus dramatically alters expression of homeostatic chemokines and dendritic cell markers during infection in vivo. Choi YK, et al. Blood, 2003 Mar 1. PMID 12406887
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables (1->3)-beta-D-glucan binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pattern recognition receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to molecule of fungal origin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of fungus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of molecule of fungal origin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis, recognition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytokine production involved in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of killing of cells of another organism IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of lymphocyte activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of wound healing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-type lectin domain family 7 member A
    Names
    DC-associated C-type lectin 1
    dectin-1
    dendritic cell-associated C-type lectin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032943.1 → NP_001028115.1  C-type lectin domain family 7 member A

      See identical proteins and their annotated locations for NP_001028115.1

      Status: PROVISIONAL

      Source sequence(s)
      AF508729
      UniProtKB/Swiss-Prot
      Q8HZR8
      UniProtKB/TrEMBL
      F6WM95
      Related
      ENSMMUP00000002925.3, ENSMMUT00000003099.4
      Conserved Domains (2) summary
      cd03593
      Location:120 → 243
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:40 → 67
      Ly49; Ly49-like protein, N-terminal region

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      9579997..9592761
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150992.2 → XP_015006478.2  C-type lectin domain family 7 member A isoform X2

      Conserved Domains (2) summary
      pfam08391
      Location:49 → 76
      Ly49; Ly49-like protein, N-terminal region
      cl02432
      Location:129 → 173
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    2. XM_015150991.2 → XP_015006477.2  C-type lectin domain family 7 member A isoform X1

      Conserved Domains (2) summary
      cd03593
      Location:83 → 206
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:49 → 76
      Ly49; Ly49-like protein, N-terminal region

    3. XM_015150993.2 → XP_015006479.2  C-type lectin domain family 7 member A isoform X3

      Conserved Domains (2) summary
      pfam08391
      Location:49 → 76
      Ly49; Ly49-like protein, N-terminal region
      cl02432
      Location:83 → 127
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8HZR8.1 GenPept UniProtKB/Swiss-Prot:Q8HZR8

    Gene LinkOut

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