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    ARFGEF3 ARFGEF family member 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703791, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARFGEF3provided by VGNC
    Official Full Name
    ARFGEF family member 3provided by VGNC
    Primary source
    VGNC:VGNC:69877
    See related
    Ensembl:ENSMMUG00000019927
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    KIAA1244
    Orthologs
    human mouse all
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    Genomic context

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    See ARFGEF3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (41772021..41956425)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (128962533..129148112, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene p53 apoptosis effector related to PMP22 Neighboring gene prostate and breast cancer overexpressed 1 Neighboring gene uncharacterized LOC114677504 Neighboring gene small integral membrane protein 28 Neighboring gene heme binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    brefeldin A-inhibited guanine nucleotide-exchange protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      41772021..41956425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001095348.4 → XP_001095348.2  brefeldin A-inhibited guanine nucleotide-exchange protein 3 isoform X1

      See identical proteins and their annotated locations for XP_001095348.2

      UniProtKB/TrEMBL
      H9FXJ4
      Related
      ENSMMUP00000026187.4, ENSMMUT00000027992.4
      Conserved Domains (3) summary
      smart00222
      Location:586 → 798
      Sec7; Sec7 domain
      pfam09324
      Location:1246 → 1303
      DUF1981; Domain of unknown function (DUF1981)
      pfam16213
      Location:5 → 168
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    2. XM_028847156.1 → XP_028702989.1  brefeldin A-inhibited guanine nucleotide-exchange protein 3 isoform X2

      UniProtKB/TrEMBL
      H9FXJ4
      Conserved Domains (4) summary
      smart00222
      Location:545 → 757
      Sec7; Sec7 domain
      PLN03076
      Location:952 → 1634
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam09324
      Location:1205 → 1262
      DUF1981; Domain of unknown function (DUF1981)
      pfam16213
      Location:5 → 121
      DCB; dimerization and cyclophilin-binding domain of Mon2

    3. XM_028847157.1 → XP_028702990.1  brefeldin A-inhibited guanine nucleotide-exchange protein 3 isoform X3

      UniProtKB/TrEMBL
      G7MQ93
      Conserved Domains (3) summary
      smart00222
      Location:451 → 663
      Sec7; Sec7 domain
      PLN03076
      Location:858 → 1540
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam09324
      Location:1111 → 1168
      DUF1981; Domain of unknown function (DUF1981)
    Nucleotide Protein
    Heading Accession and Version

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