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    PIAS1 protein inhibitor of activated STAT 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693445, updated on 17-Aug-2024

    Summary

    Official Symbol
    PIAS1provided by VGNC
    Official Full Name
    protein inhibitor of activated STAT 1provided by VGNC
    Primary source
    VGNC:VGNC:75876
    Locus tag
    EGK_17624
    See related
    Ensembl:ENSMMUG00000011699
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    NEW
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    Genomic context

    See PIAS1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (44715594..44852051)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (44964824..45101093)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S15a-like Neighboring gene calmodulin like 4 Neighboring gene CLN6 transmembrane ER protein Neighboring gene uncharacterized LOC114679431

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO ligase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 SUMO-protein ligase PIAS1
    Names
    Protein inhibitor of activated STAT protein 1
    NP_001253230.1
    XP_028705986.1
    XP_028705987.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266301.2NP_001253230.1  E3 SUMO-protein ligase PIAS1

      See identical proteins and their annotated locations for NP_001253230.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048538
      UniProtKB/TrEMBL
      A0A8J8XWD1, F7HEF1, F7HEF3, G7MY21
      Related
      ENSMMUP00000015356.2, ENSMMUT00000016388.4
      Conserved Domains (3) summary
      smart00513
      Location:1145
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:332379
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:137285
      PINIT; PINIT domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      44715594..44852051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028850154.1XP_028705987.1  E3 SUMO-protein ligase PIAS1 isoform X2

      UniProtKB/TrEMBL
      F7HEF1
      Conserved Domains (3) summary
      smart00513
      Location:1145
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:332379
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:137280
      PINIT; PINIT domain
    2. XM_028850153.1XP_028705986.1  E3 SUMO-protein ligase PIAS1 isoform X1

      UniProtKB/TrEMBL
      F7HEF1
      Related
      ENSMMUP00000015357.3, ENSMMUT00000016389.4
      Conserved Domains (3) summary
      smart00513
      Location:236
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:323370
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:128276
      PINIT; PINIT domain