MICB MHC class I polypeptide-related sequence B [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: MICB
Gene description: MHC class I polypeptide-related sequence B
See related: Ensembl:ENSMMUG00000006609
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: MIC2; mamu-MICB
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Genomic context

Location:: chromosome: 4

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	4	NC_041757.1 (138011137..138023267, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	4	NC_027896.1 (32312156..32362974)

Chromosome 4 - NC_041757.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables peptide antigen binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	IEA Inferred from Electronic Annotation more info	PubMed
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell mediated cytotoxicity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: MHC class I polypeptide-related sequence B

Names: MHC class I related protein; MHC class I-related chain; MIC class I antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001114956.1 → NP_001108428.1 MHC class I polypeptide-related sequence B precursor

See identical proteins and their annotated locations for NP_001108428.1

Status: PROVISIONAL

Source sequence(s)

AB128049

UniProtKB/TrEMBL

A0A5F8AB90, Q5TM16

Related

ENSMMUP00000074652.1, ENSMMUT00000079535.1

Conserved Domains (2) summary

cd07698
Location:205 → 296

IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain

cl08246
Location:31 → 156

MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2