U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ADRA1A adrenoceptor alpha 1A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712509, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ADRA1Aprovided by VGNC
    Official Full Name
    adrenoceptor alpha 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:69721
    Locus tag
    EGK_18793
    See related
    Ensembl:ENSMMUG00000023112
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ADRA1A in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (27023459..27137314, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (26784545..26898932, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene PNMA family member 2 Neighboring gene dihydropyrimidinase like 2 Neighboring gene proteasome activator complex subunit 2 pseudogene Neighboring gene 60S acidic ribosomal protein P1 pseudogene Neighboring gene uncharacterized LOC114680209 Neighboring gene uncharacterized LOC106999712 Neighboring gene uncharacterized LOC106999713

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cloning, expression and immunolocalization of alpha1-adrenoceptor in different tissues from rhesus monkey and human male reproductive tract. Patrão MT, et al. Mol Hum Reprod, 2008 Feb. PMID 18204069
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha1-adrenergic receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cardiac muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    alpha-1A adrenergic receptor
    Names
    adrenergic, alpha-1A-, receptor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114733.1 → NP_001108205.1  alpha-1A adrenergic receptor

      See identical proteins and their annotated locations for NP_001108205.1

      Status: PROVISIONAL

      Source sequence(s)
      AY513585
      UniProtKB/TrEMBL
      B0S4P2, B0S4P8, G7N0R5
      Conserved Domains (1) summary
      cd15325
      Location:27 → 337
      7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      27023459..27137314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015145004.2 → XP_015000490.1  alpha-1A adrenergic receptor isoform X3

      UniProtKB/TrEMBL
      A0A1D5Q9G7, B0S4P6, B0S4P8
      Related
      ENSMMUP00000044685.2, ENSMMUT00000066065.2
      Conserved Domains (2) summary
      pfam00001
      Location:43 → 326
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:37 → 341
      7tm_4; Olfactory receptor

    2. XM_015145002.2 → XP_015000488.1  alpha-1A adrenergic receptor isoform X2

      UniProtKB/TrEMBL
      A0A1D5RF92, B0S4P8
      Related
      ENSMMUP00000058986.2, ENSMMUT00000077920.2
      Conserved Domains (2) summary
      pfam00001
      Location:43 → 326
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:37 → 341
      7tm_4; Olfactory receptor

    3. XM_015145005.2 → XP_015000491.1  alpha-1A adrenergic receptor isoform X4

      UniProtKB/TrEMBL
      B0S4P8
      Conserved Domains (2) summary
      pfam00001
      Location:43 → 326
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:37 → 341
      7tm_4; Olfactory receptor

    4. XM_015145001.2 → XP_015000487.1  alpha-1A adrenergic receptor isoform X1

      UniProtKB/TrEMBL
      B0S4P2, B0S4P8, G7N0R5
      Conserved Domains (1) summary
      cd15325
      Location:27 → 337
      7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

    5. XM_028852260.1 → XP_028708093.1  alpha-1A adrenergic receptor isoform X1

      UniProtKB/TrEMBL
      B0S4P2, B0S4P8, G7N0R5
      Conserved Domains (1) summary
      cd15325
      Location:27 → 337
      7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.