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    ITPR2 inositol 1,4,5-trisphosphate receptor type 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708714, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITPR2provided by VGNC
    Official Full Name
    inositol 1,4,5-trisphosphate receptor type 2provided by VGNC
    Primary source
    VGNC:VGNC:73805
    See related
    Ensembl:ENSMMUG00000023128
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITPR2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    60
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (27644569..28141361, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (27280943..27778644, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix family member e41 Neighboring gene sarcospan Neighboring gene eukaryotic initiation factor 4A-III pseudogene Neighboring gene protein tyrosine phosphatase type IVA 1 pseudogene Neighboring gene translation initiation factor IF-2-like Neighboring gene integrator complex subunit 13 Neighboring gene FGFR1 oncogene partner 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol 1,4,5 trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inositol 1,4,5-trisphosphate-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol 1,4,5-trisphosphate receptor type 2
    Names
    inositol 1,4,5-triphosphate receptor, type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      27644569..28141361 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151322.2 → XP_015006808.2  inositol 1,4,5-trisphosphate receptor type 2 isoform X1

      UniProtKB/TrEMBL
      F7DGC2
      Conserved Domains (5) summary
      pfam01365
      Location:472 → 669
      RYDR_ITPR; RIH domain
      pfam08454
      Location:1916 → 2021
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
      pfam00520
      Location:2289 → 2551
      Ion_trans; Ion transport protein
      pfam02815
      Location:232 → 431
      MIR; MIR domain

    2. XM_028829349.1 → XP_028685182.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X2

      UniProtKB/TrEMBL
      F7A818, F7DGC2, H9FU41
      Related
      ENSMMUP00000040070.3, ENSMMUT00000047039.3
      Conserved Domains (5) summary
      pfam01365
      Location:472 → 669
      RYDR_ITPR; RIH domain
      pfam08454
      Location:1916 → 2021
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
      pfam00520
      Location:2289 → 2551
      Ion_trans; Ion transport protein
      pfam02815
      Location:232 → 431
      MIR; MIR domain

    3. XM_028829350.1 → XP_028685183.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X3

      UniProtKB/TrEMBL
      F7DGC2
      Conserved Domains (5) summary
      pfam01365
      Location:288 → 485
      RYDR_ITPR; RIH domain
      pfam08454
      Location:1732 → 1837
      RIH_assoc; RyR and IP3R Homology associated
      cl19745
      Location:2 → 41
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
      pfam00520
      Location:2105 → 2367
      Ion_trans; Ion transport protein
      pfam02815
      Location:48 → 247
      MIR; MIR domain

    4. XM_028829352.1 → XP_028685185.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZV14, F7DGC2
      Related
      ENSMMUP00000068480.1, ENSMMUT00000081435.1
      Conserved Domains (5) summary
      pfam01365
      Location:472 → 669
      RYDR_ITPR; RIH domain
      pfam08454
      Location:1916 → 2021
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
      pfam00520
      Location:2289 → 2431
      Ion_trans; Ion transport protein
      pfam02815
      Location:232 → 431
      MIR; MIR domain
    Nucleotide Protein
    Heading Accession and Version

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